Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | KDM1A | O60341 | 1/20 | 0.33 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8042055 | 0.84 | S1PR4 (0.40) | HTTTP53 | |
| SCHEMBL8463202 | 0.81 | MAPT (0.43) | ALDH1A1NPC1RAB9AMAPTSMN1; SMN2 | |
| SCHEMBL8034546 | 0.79 | RXRA (0.36) | KDM1ARCOR1HPGDHTTTP53 | |
| SCHEMBL8036387 | 0.77 | — | — | |
| SCHEMBL8024723 | 0.73 | ALOX15 (0.36) | KDM1AALOX15 | |
| SCHEMBL8055080 | 0.68 | GPBAR1 (0.35) | ALDH1A1KDM1ARCOR1 | |
| SCHEMBL17803643 | 0.65 | RAB9A (0.58) | NPC1RAB9ASMN1; SMN2HPGDHDAC8 | |
| SCHEMBL8461900 | 0.62 | TSHR (0.46) | NPC1RAB9AALOX15NPSR1MEN1 | |
| SCHEMBL13885119 | 0.62 | ALDH1A1 (0.50) | ALDH1A1NPC1RAB9AMAPTSMN1; SMN2 | |
| SCHEMBL8036369 | 0.60 | MAOB (0.42) | MAOBKDM1ATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0915831-A1 | NOVEL METHOD FOR PREPARING AROMATIC AMIDES AND INTERMEDIATES THEREFOR | Hoechst Schering AgrEvo S.A. (FR) | 1999-05-19 | — | — | EP | disclosed |
| WO-1998003470-A1 | NOVEL METHOD FOR PREPARING AROMATIC AMIDES AND INTERMEDIATES THEREFOR | HOECHST SCHERING AGREVO S.A. (FR) | 1998-01-29 | — | — | WO | disclosed |