SCHEMBL8468401

SCHEMBL8468401

CCCC1CCCCN(O)C1=O

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ENO1 P06733 3/20 0.40
CYP3A4 P08684 1/20 0.37
TSHR P16473 1/20 0.37
TDP1 Q9NUW8 1/20 0.37
MAPT P10636 1/20 0.37
APEX1 P27695 1/20 0.37
MMP2 P08253 1/20 0.35
MMP9 P14780 1/20 0.35
OPRM1 P35372 1/20 0.34
OPRL1 P41146 1/20 0.34
ACE P12821 1/20 0.33
CA1 P00915 1/20 0.33
CA2 P00918 1/20 0.33
CA4 P22748 1/20 0.33
PSEN1 P49768 1/20 0.33
PSEN2 P49810 1/20 0.33
APH1B Q8WW43 1/20 0.33
NCSTN Q92542 1/20 0.33
APH1A Q96BI3 1/20 0.33
PSENEN Q9NZ42 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6294033 0.85 ENO1 (0.42) ENO1CYP3A4TSHRTDP1MAPT
SCHEMBL13074068 0.84 ENO1 (0.41) ENO1CYP3A4TSHRTDP1MAPT
SCHEMBL10491064 0.80 OPRM1 (0.35) OPRM1OPRL1PSEN1PSEN2APH1B
SCHEMBL13074065 0.79 ENO1 (0.47) ENO1CYP3A4TSHRTDP1MAPT
SCHEMBL28636739 0.77 ENO1 (0.39) ENO1CYP3A4TSHRTDP1MAPT
SCHEMBL28357676 0.77 ACE (0.37) ACEPSEN1PSEN2APH1BNCSTN
SCHEMBL7238109 0.75 CHRNB2 (0.34) OPRM1OPRL1PSEN1PSEN2APH1B
SCHEMBL18068264 0.74 ACE (0.35) OPRM1OPRL1ACE
SCHEMBL18068273 0.74 ACE (0.35) OPRM1OPRL1ACE
SCHEMBL28354693 0.72 GBA1 (0.42) CHRNB2CHRNA7CHRNA4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12497478-B2 High molecular weight block copolymers comprising repeating units derived from monomers comprising lactam and acryloyl moieties and hydrophilic monomers, compositions, and applications thereof ISP INVESTMENTS LLC (US) 2025-12-16 US disclosed
WO-2025024325-A2 ALL-ACRYLIC TRIBLOCK AND TETRABLOCK COPOLYMERS HAVING A LACTAM MOIETY AND APPLICATIONS THEREOF ISP INVESTMENTS LLC (US) 2025-01-30 WO disclosed
US-20250032398-A1 HIGH MOLECULAR WEIGHT BLOCK COPOLYMERS COMPRISING REPEATING UNITS DERIVED FROM MONOMERS COMPRISING LACTAM AND ACRYLOYL MOIETIES AND HYDROPHILIC MONOMERS, COMPOSITIONS, AND APPLICATIONS THEREOF ISP INVESTMENTS LLC (US) 2025-01-30 US disclosed
US-11859029-B2 Methods of synthesis of homopolymers and non-homopolymers comprising repeating units derived from monomers comprising lactam and acryloyl moieties in an aqueous medium ISP INVESTMENTS LLC (US) 2024-01-02 US disclosed
US-10905636-B2 Block copolymers comprising repeating units derived from monomers comprising lactam and acryloyl moieties and hydrophobic monomers, compositions, and applications thereof ISP INVESTMENTS LLC (US) 2021-02-02 US disclosed
US-20200407470-A1 METHODS OF SYNTHESIS OF HOMOPOLYMERS AND NON-HOMOPOLYMERS COMPRISING REPEATING UNITS DERIVED FROM MONOMERS COMPRISING LACTAM AND ACRYLOYL MOIETIES IN AN AQUEOUS MEDIUM ISP INVESTMENTS LLC (US) 2020-12-31 US disclosed
US-20190382519-A1 CROSS-LINKED BLOCK COPOLYMERS COMPRISING REPEATING UNITS DERIVED FROM MONOMERS COMPRISING LACTAM AND ACRYLOYL MOIETIES, COMPOSITIONS, AND APPLICATIONS THEREOF ISP INVESTMENTS LLC (US) 2019-12-19 US disclosed
US-20190015304-A1 BLOCK COPOLYMERS COMPRISING REPEATING UNITS DERIVED FROM MONOMERS COMPRISING LACTAM AND ACRYLOYL MOIETIES AND HYDROPHOBIC MONOMERS, COMPOSITIONS, AND APPLICATIONS THEREOF ISP INVESTMENTS LLC (US) 2019-01-17 US disclosed
WO-2018132548-A1 CROSS-LINKED BLOCK COPOLYMERS COMPRISING REPEATING UNITS DERIVED FROM MONOMERS COMPRISING LACTAM AND ACRYLOYL MOIETIES, COMPOSITIONS, AND APPLICATIONS THEREOF ISP INVESTMENTS LLC (US) 2018-07-19 WO disclosed
WO-2018132370-A1 HIGH MOLECULAR WEIGHT BLOCK COPOLYMERS COMPRISING REPEATING UNITS DERIVED FROM MONOMERS COMPRISING LACTAM AND ACRYLOYL MOIETIES AND HYDROPHILIC MONOMERS, COMPOSITIONS, AND APPLICATIONS THEREOF ISP INVESTMENTS LLC (US) 2018-07-19 WO disclosed
WO-2017123572-A1 BLOCK COPOLYMERS COMPRISING REPEATING UNITS DERIVED FROM MONOMERS COMPRISING LACTAM AND ACRYLOYL MOIETIES AND HYDROPHOBIC MONOMERS, COMPOSITIONS, AND APPLICATIONS THEREOF ISP INVESTMENTS LLC (US) 2017-07-20 WO disclosed
US-5959001-A LOW VISCOSITY; MIXTURE CONTAINING PIGMENT, PASTE-MAKING AGENT, AMINE OR SALT, ADDITION HOMO- OR COPOLYMER BAYER AKTIENGESELLSCHAFT (DE) 1999-09-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12497478-B2 High molecular weight block copolymers comprising repeating units derived from monomers comprising lactam and acryloyl moieties and hydrophilic monomers, compositions, and applications thereof MRPL9, PRMT9, MRPL19 ENO1 4402/4885CYP3A4 4305/4885TSHR 1038/4885
US-20190015304-A1 BLOCK COPOLYMERS COMPRISING REPEATING UNITS DERIVED FROM MONOMERS COMPRISING LACTAM AND ACRYLOYL MOIETIES AND HYDROPHOBIC MONOMERS, COMPOSITIONS, AND APPLICATIONS THEREOF F9, ADCY9, MMS19 ENO1 4335/4885CYP3A4 3430/4885TSHR 1628/4885
US-10905636-B2 Block copolymers comprising repeating units derived from monomers comprising lactam and acryloyl moieties and hydrophobic monomers, compositions, and applications thereof F9, ADCY9, MMS19 ENO1 4335/4885CYP3A4 3430/4885TSHR 1628/4885
US-20190382519-A1 CROSS-LINKED BLOCK COPOLYMERS COMPRISING REPEATING UNITS DERIVED FROM MONOMERS COMPRISING LACTAM AND ACRYLOYL MOIETIES, COMPOSITIONS, AND APPLICATIONS THEREOF ADSL, ABHD6, APH1B ENO1 4474/4885CYP3A4 3142/4885TSHR 4275/4885
US-20250032398-A1 HIGH MOLECULAR WEIGHT BLOCK COPOLYMERS COMPRISING REPEATING UNITS DERIVED FROM MONOMERS COMPRISING LACTAM AND ACRYLOYL MOIETIES AND HYDROPHILIC MONOMERS, COMPOSITIONS, AND APPLICATIONS THEREOF PCNA, ADSL, APH1B ENO1 4381/4885CYP3A4 3590/4885TSHR 3587/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.