SCHEMBL847879

SCHEMBL847879

CC1(C(=O)OCCCCl)COC(=O)OC1

nearest known ligand 0.34

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
ATM Q13315 1/20 0.32
PRKCA P17252 3/20 0.32
PSEN1 P49768 3/20 0.31
ABCB11 O95342 1/20 0.30
LMNA P02545 1/20 0.30
MAPT P10636 1/20 0.30
MAPK1 P28482 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16154063 0.94 PRKCA (0.35) ATMPRKCAPSEN1ABCB11LMNA
SCHEMBL16154064 0.94 PRKCA (0.35) ATMPRKCAPSEN1ABCB11LMNA
SCHEMBL10314811 0.86 PRKCA (0.40) ATMPRKCAPSEN1LMNAMAPK1
SCHEMBL16174554 0.84 ATM (0.32) ATMPRKCA
SCHEMBL847093 0.84 ATM (0.32) ATMPRKCA
SCHEMBL17304880 0.84 ATM (0.32) ATMPRKCA
SCHEMBL17928871 0.84 ATM (0.32) ATMPRKCA
SCHEMBL13539366 0.83 PRKCA (0.47) PRKCAPSEN1
SCHEMBL1537680 0.83 PRKCA (0.47) PRKCAPSEN1
SCHEMBL17803931 0.83 PRKCA (0.47) PRKCAPSEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 232 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11690380-B2 Antimicrobial guanidinium and thiouronium functionalized polymers CORAL BAY II, LLC (US) 2023-07-04 US disclosed
US-11180608-B2 Biodegradable polymers, complexes thereof for gene therapeutics and drug delivery, and methods related thereto INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2021-11-23 US disclosed
US-11180608-B2 Biodegradable polymers, complexes thereof for gene therapeutics and drug delivery, and methods related thereto INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2021-11-23 US disclosed
US-11149114-B2 Biodegradable polymers, complexes thereof for gene therapeutics and drug delivery, and methods related thereto INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2021-10-19 US disclosed
US-11149114-B2 Biodegradable polymers, complexes thereof for gene therapeutics and drug delivery, and methods related thereto INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2021-10-19 US disclosed
US-11116844-B2 Macromolecular chemotherapeutics INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2021-09-14 US disclosed
US-10980234-B2 Antimicrobial guanidinium and thiouronium functionalized polymers CORAL BAY II, LLC (US) 2021-04-20 US disclosed
US-10786530-B2 Antimicrobial cationic polycarbonates INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2020-09-29 US disclosed
US-20200079901-A1 BIODEGRADABLE POLYMERS, COMPLEXES THEREOF FOR GENE THERAPEUTICS AND DRUG DELIVERY, AND METHODS RELATED THERETO INTERNATIONAL BUSINESS MACHINES CORPORATION 2020-03-12 US disclosed
US-10463746-B2 Macromolecular chemotherapeutics INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2019-11-05 US disclosed
US-20110151566-A1 BIODEGRADABLE POLYMERS, COMPLEXES THEREOF FOR GENE THERAPEUTICS AND DRUG DELIVERY, AND METHODS RELATED THERETO AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) 2011-06-23 US disclosed
US-20110151566-A1 BIODEGRADABLE POLYMERS, COMPLEXES THEREOF FOR GENE THERAPEUTICS AND DRUG DELIVERY, AND METHODS RELATED THERETO AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) 2011-06-23 US disclosed
US-20110151566-A1 BIODEGRADABLE POLYMERS, COMPLEXES THEREOF FOR GENE THERAPEUTICS AND DRUG DELIVERY, AND METHODS RELATED THERETO AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) 2011-06-23 US disclosed
US-20110152167-A1 BIODEGRADABLE BLOCK POLYMERS FOR DRUG DELIVERY, AND METHODS RELATED THERETO AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) 2011-06-23 US disclosed
US-20110152167-A1 BIODEGRADABLE BLOCK POLYMERS FOR DRUG DELIVERY, AND METHODS RELATED THERETO AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) 2011-06-23 US disclosed
US-20110150977-A1 ANTIMICROBIAL POLYMERS AND METHODS OF MANUFACTURE THEREOF AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) 2011-06-23 US disclosed
US-20110150977-A1 ANTIMICROBIAL POLYMERS AND METHODS OF MANUFACTURE THEREOF AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) 2011-06-23 US disclosed
US-20110150977-A1 ANTIMICROBIAL POLYMERS AND METHODS OF MANUFACTURE THEREOF AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) 2011-06-23 US disclosed
US-20100305281-A1 POLYMERS BEARING PENDANT PENTAFLUOROPHENYL ESTER GROUPS, AND METHODS OF SYNTHESIS AND FUNCTIONALIZATION THEREOF INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2010-12-02 US disclosed
US-20100305281-A1 POLYMERS BEARING PENDANT PENTAFLUOROPHENYL ESTER GROUPS, AND METHODS OF SYNTHESIS AND FUNCTIONALIZATION THEREOF INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2010-12-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (11 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200079901-A1 BIODEGRADABLE POLYMERS, COMPLEXES THEREOF FOR GENE THERAPEUTICS AND DRUG DELIVERY, AND METHODS RELATED THERETO DCLRE1A, ODC1, MRTO4 ATM 4063/4885PRKCA 3882/4885PSEN1 4146/4885
US-11116844-B2 Macromolecular chemotherapeutics DCK, CRKL, DTYMK ATM 1836/4885PRKCA 2868/4885PSEN1 3635/4885
US-11149114-B2 Biodegradable polymers, complexes thereof for gene therapeutics and drug delivery, and methods related thereto DCLRE1A, ODC1, MRTO4 ATM 4063/4885PRKCA 3882/4885PSEN1 4146/4885
US-11180608-B2 Biodegradable polymers, complexes thereof for gene therapeutics and drug delivery, and methods related thereto DCLRE1A, ODC1, MRTO4 ATM 4063/4885PRKCA 3882/4885PSEN1 4146/4885
US-10980234-B2 Antimicrobial guanidinium and thiouronium functionalized polymers PUF60, CAPG, GMPS ATM 3036/4885PRKCA 1616/4885PSEN1 3868/4885
US-11690380-B2 Antimicrobial guanidinium and thiouronium functionalized polymers PUF60, CAPG, GMPS ATM 3036/4885PRKCA 1616/4885PSEN1 3868/4885
US-20110150977-A1 ANTIMICROBIAL POLYMERS AND METHODS OF MANUFACTURE THEREOF MLEC, NOD2, PAM ATM 4539/4885PRKCA 2786/4885PSEN1 4629/4885
US-20100305281-A1 POLYMERS BEARING PENDANT PENTAFLUOROPHENYL ESTER GROUPS, AND METHODS OF SYNTHESIS AND FUNCTIONALIZATION THEREOF PFAS, PAM, PCNA ATM 3376/4885PRKCA 2976/4885PSEN1 4546/4885
US-10786530-B2 Antimicrobial cationic polycarbonates VDR, GC, CYP24A1 ATM 4846/4885PRKCA 1780/4885PSEN1 4757/4885
US-20110152167-A1 BIODEGRADABLE BLOCK POLYMERS FOR DRUG DELIVERY, AND METHODS RELATED THERETO SAMM50, ADRM1, UFM1 ATM 444/4885PRKCA 3565/4885PSEN1 3646/4885
US-10463746-B2 Macromolecular chemotherapeutics DCK, CRKL, DTYMK ATM 1836/4885PRKCA 2868/4885PSEN1 3635/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.