Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PER2 | O15055 | 4/20 | 0.51 |
| ▸ | CRY1 | Q16526 | 3/20 | 0.51 |
| ▸ | CRY2 | Q49AN0 | 3/20 | 0.51 |
| ▸ | BACE1 | P56817 | 7/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | CASP1 | P29466 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | RORC | P51449 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8484814 | 0.90 | CRY1 (0.49) | PER2CRY1CRY2BACE1LMNA | |
| SCHEMBL8486007 | 0.90 | LMNA (0.44) | PER2CRY1CRY2BACE1LMNA | |
| SCHEMBL8488567 | 0.83 | PER2 (0.34) | PER2CRY1CRY2 | |
| SCHEMBL8488046 | 0.81 | PER2 (0.42) | PER2CRY1CRY2LMNASMN1; SMN2 | |
| SCHEMBL8486390 | 0.81 | S1PR1 (0.36) | PER2CRY1CRY2 | |
| SCHEMBL8489654 | 0.81 | S1PR1 (0.36) | PER2CRY1CRY2 | |
| SCHEMBL8488572 | 0.76 | BACE1 (0.48) | PER2CRY1CRY2BACE1LMNA | |
| SCHEMBL8489489 | 0.76 | CRY1 (0.60) | PER2CRY1CRY2BACE1SMN1; SMN2 | |
| SCHEMBL8489557 | 0.75 | PER2 (0.55) | PER2CRY1CRY2BACE1ALOX15 | |
| SCHEMBL9004320 | 0.74 | PER2 (0.46) | PER2CRY1CRY2BACE1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5919431-A | 1,4,7,10-tetraazacyclododecane derivatives, their use, pharmaceutical agents containing these compounds and process for their production | SCHERING AKTIENGESELLSCHAFT (DE) | 1999-07-06 | — | — | US | disclosed |