Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM2 | P50570 | 3/20 | 0.42 |
| ▸ | EHMT2 | Q96KQ7 | 3/20 | 0.38 |
| ▸ | EHMT1 | Q9H9B1 | 3/20 | 0.38 |
| ▸ | GBA1 | P04062 | 1/20 | 0.38 |
| ▸ | TYRO3 | Q06418 | 8/20 | 0.37 |
| ▸ | MERTK | Q12866 | 8/20 | 0.37 |
| ▸ | GAS6 | Q14393 | 8/20 | 0.37 |
| ▸ | FLT3 | P36888 | 7/20 | 0.37 |
| ▸ | AXL | P30530 | 2/20 | 0.37 |
| ▸ | KCNH3 | Q9ULD8 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | BCL6 | P41182 | 1/20 | 0.36 |
| ▸ | STK17A | Q9UEE5 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3455242 | 0.70 | ULK1 (0.41) | DNM2TYRO3MERTKGAS6FLT3 | |
| SCHEMBL18611842 | 0.68 | DNM2 (0.47) | DNM2KCNH3KMT2ANPSR1 | |
| SCHEMBL13195759 | 0.68 | L3MBTL1 (0.52) | STK17A | |
| SCHEMBL8840402 | 0.68 | HTR1A (0.48) | DNM2HTT | |
| SCHEMBL516082 | 0.67 | KCNH3 (0.54) | DNM2KCNH3KMT2AMAPTHTT | |
| SCHEMBL10531678 | 0.67 | DNM2 (0.44) | DNM2TYRO3MERTKGAS6FLT3 | |
| SCHEMBL10502792 | 0.67 | DNM2 (0.44) | DNM2TYRO3MERTKGAS6FLT3 | |
| SCHEMBL10504062 | 0.67 | DNM2 (0.44) | DNM2TYRO3MERTKGAS6FLT3 | |
| SCHEMBL10503228 | 0.67 | DNM2 (0.44) | DNM2TYRO3MERTKGAS6FLT3 | |
| SCHEMBL10502394 | 0.67 | DNM2 (0.44) | DNM2TYRO3MERTKGAS6FLT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5925644-A | CONTROLLING ANIMAL PESTS, SUCH AS INSECTS, ARACHNIDS, NEMATODES, HELMINTHS AND MOLLUSCS, FOR CONTROLLING ENDOPARASITES AND ECTOPARASITES IN THE VETERINARY FIELD, AND FOR CONTROLLING HARMFUL FUNGI | HOECHST SCHERING AGREVO GMBH (DE) | 1999-07-20 | — | — | US | disclosed |