Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 known ✓ | P04150 | 1/20 | 0.32 |
| ▸ | ADORA3 known ✓ | P0DMS8 | 1/20 | 0.32 |
| ▸ | PTGS1 known ✓ | P23219 | 1/20 | 0.32 |
| ▸ | PDE4A known ✓ | P27815 | 1/20 | 0.32 |
| ▸ | PDE4D known ✓ | Q08499 | 1/20 | 0.32 |
| ▸ | THRB known ✓ | P10828 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | SHBG | P04278 | 1/20 | 0.38 |
| ▸ | MDH1 | P40925 | 8/20 | 0.35 |
| ▸ | MDH2 | P40926 | 8/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.32 |
| ▸ | ELANE | P08246 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 3/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | APAF1 | O14727 | 2/20 | 0.32 |
| ▸ | USP2 | O75604 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Potassium Ion SCHEMBL4542314 | 0.97 | CYP3A4 (0.41) | CYP3A4SMN1; SMN2SHBGMDH1MDH2 | |
| SCHEMBL9395351 | 0.84 | CYP3A4 (0.49) | CYP3A4SMN1; SMN2SHBGMDH1MDH2 | |
| SCHEMBL9632633 | 0.79 | CYP3A4 (0.46) | CYP3A4SMN1; SMN2SHBGMDH1MDH2 | |
| SCHEMBL8506133 | 0.77 | CYP3A4 (0.54) | CYP3A4SMN1; SMN2SHBGMDH1MDH2 | |
| Potassium Ion SCHEMBL4542321 | 0.75 | CYP3A4 (0.54) | CYP3A4SMN1; SMN2SHBGMDH1MDH2 | |
| SCHEMBL18844500 | 0.74 | CYP3A4 (0.54) | CYP3A4SMN1; SMN2SHBGMDH1MDH2 | |
| SCHEMBL24564756 | 0.74 | CYP3A4 (0.47) | CYP3A4SMN1; SMN2SHBGMDH1MDH2 | |
| SCHEMBL4619376 | 0.71 | CYP3A4 (0.56) | CYP3A4SMN1; SMN2SHBGMDH1MDH2 | |
| SCHEMBL5617338 | 0.71 | FUT7 (0.46) | CYP3A4SMN1; SMN2SHBGHIF1AMEN1 | |
| SCHEMBL28632506 | 0.70 | CYP3A4 (0.53) | CYP3A4SMN1; SMN2SHBGMDH1MDH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0911690-A1 | Photothermographic elements adapted for laser exposure | FUJI PHOTO FILM CO., LTD. (JP) | 1999-04-28 | — | — | EP | disclosed |