Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A12 | Q96S37 | 5/20 | 0.54 |
| ▸ | CACNA1H | O95180 | 3/20 | 0.54 |
| ▸ | CACNA1B | Q00975 | 3/20 | 0.54 |
| ▸ | MRGPRX1 | Q96LB2 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | PLA2G7 | Q13093 | 2/20 | 0.49 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.48 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.48 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | STAT3 | P40763 | 1/20 | 0.46 |
| ▸ | ACLY | P53396 | 1/20 | 0.46 |
| ▸ | PGR | P06401 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL851124 | 0.84 | PGR (0.54) | SLC22A12CACNA1HCACNA1BMEN1KMT2A | |
| SCHEMBL3792939 | 0.83 | F2 (0.62) | SLC22A12CACNA1HCACNA1BMEN1KMT2A | |
| SCHEMBL851435 | 0.79 | MRGPRX1 (0.82) | CACNA1HCACNA1BMRGPRX1FFAR1FFAR4 | |
| SCHEMBL851158 | 0.79 | ST14 (0.67) | SLC22A12CACNA1HCACNA1BMEN1KMT2A | |
| SCHEMBL7595509 | 0.78 | SLC22A12 (0.56) | SLC22A12MEN1KMT2AACLY | |
| SCHEMBL16592647 | 0.77 | ATIC (0.56) | SLC22A12MEN1KMT2AACLY | |
| SCHEMBL14087603 | 0.76 | CYP2C9 (0.65) | KDM4EALDH1A1 | |
| SCHEMBL850766 | 0.75 | PGR (0.54) | SLC22A12CACNA1HCACNA1BMRGPRX1ACLY | |
| SCHEMBL851768 | 0.75 | MRGPRX1 (0.66) | CACNA1HCACNA1BMRGPRX1KMT2AFFAR1 | |
| SCHEMBL7127256 | 0.74 | CCR2 (0.61) | CACNA1HCACNA1BSTAT3ACLY |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140200225-A1 | PROTEASE INHIBITORS | ORION CORPORATION (FI) | 2014-07-17 | — | — | US | disclosed |
| US-8722930-B2 | Protease inhibitors | ORION CORPORATION (FI) | 2014-05-13 | — | — | US | disclosed |
| US-20120136002-A1 | PROTEASE INHIBITORS | AURIGENE DISCOVERY TECHNOLOGIES LIMITED (IN) | 2012-05-31 | — | — | US | disclosed |
| EP-2432556-A1 | PROTEASE INHIBITORS | Orion Corporation (FI) | 2012-03-28 | — | — | EP | disclosed |
| WO-2010133748-A1 | PROTEASE INHIBITORS | ORION CORPORATION (FI) | 2010-11-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140200225-A1 | PROTEASE INHIBITORS | SERPINB1, TMPRSS15, PRSS1 | SLC22A12 2661/4885CACNA1H 3794/4885CACNA1B 3892/4885 |
| US-20120136002-A1 | PROTEASE INHIBITORS | SERPINB1, TMPRSS15, PRSS1 | SLC22A12 2661/4885CACNA1H 3794/4885CACNA1B 3892/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.