Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SQOR | Q9Y6N5 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.34 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.34 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.34 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.34 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.33 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.33 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6818541 | 0.82 | HPGD (0.33) | KDM4EMEN1KMT2AMAPK1HSD17B10 | |
| SCHEMBL21728097 | 0.68 | AR (0.44) | KDM4EMAPTMEN1GAAKMT2A | |
| SCHEMBL6550839 | 0.67 | TRPV4 (0.38) | KDM4EMAPTMEN1GAAKMT2A | |
| SCHEMBL3275986 | 0.67 | ADRA2A (0.50) | KDM4EMAPTSMN1; SMN2MEN1NPC1 | |
| SCHEMBL506595 | 0.64 | ALDH1A1 (0.42) | KDM4EMEN1GAAKMT2AMAPK1 | |
| SCHEMBL22140450 | 0.64 | TRPV4 (0.43) | KDM4EMEN1GAAKMT2AHPGD | |
| SCHEMBL28410677 | 0.63 | MAOA (0.57) | KDM4EMAPTSMN1; SMN2NPC1KMT2A | |
| SCHEMBL18992094 | 0.63 | SQOR (0.41) | SQORKDM4EMAPTSMN1; SMN2MEN1 | |
| SCHEMBL9469860 | 0.62 | SQOR (0.44) | SQORGAARAB9AKMT2ACYP19A1 | |
| SCHEMBL28857557 | 0.62 | HPGD (0.40) | KDM4ESMN1; SMN2GAAMAPK1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0948330-A4 | IL-8 RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORP (US) | 1999-12-01 | — | — | EP | disclosed |
| EP-0948330-A1 | IL-8 RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1999-10-13 | — | — | EP | disclosed |
| WO-1998005328-A1 | IL-8 RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1998-02-12 | — | — | WO | disclosed |