SCHEMBL8527375

SCHEMBL8527375

CC1N=Cc2ccccc21

nearest known ligand 0.33

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
HTR5A P47898 2/20 0.33
BRD4 O60885 1/20 0.32
CCL2 P13500 1/20 0.32
HTR2A P28223 1/20 0.31
CYP19A1 P11511 1/20 0.31
CYP11B1 P15538 1/20 0.31
CYP11B2 P19099 1/20 0.31
NOS3 P29474 1/20 0.31
NOS1 P29475 1/20 0.31
NOS2 P35228 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25038692 0.74 BRD4 (0.36) HTR5ABRD4CCL2HTR2A
SCHEMBL28445883 0.71 MAOA (0.33) HTR2A
SCHEMBL6045293 0.71 HTR2A (0.35) HTR2A
SCHEMBL24596781 0.71
Hydrochloric Acid SCHEMBL7724483 0.70 KDM1A (0.36) HTR2A
SCHEMBL11825016 0.69
SCHEMBL8157017 0.68 BRD4 (0.38) HTR5ABRD4CCL2HTR2A
SCHEMBL23513879 0.68 EDNRA (0.32)
SCHEMBL23264409 0.67 KDM1A (0.31)
SCHEMBL3998927 0.67 BRD4 (0.30) BRD4CCL2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240224789-A1 IONIC COMPOUND AND APPLICATION THEREOF, PEROVSKITE PRECURSOR SOLUTION, PEROVSKITE MATERIAL, SOLAR CELL, AND ELECTRIC APPARATUS CONTEMPORARY AMPEREX TECHNOLOGY (HONG KONG) LIMITED (CN) 2024-07-04 US disclosed
CN-118043309-A Ionic compound and application thereof, perovskite precursor solution, perovskite material, solar cell and electricity utilization device 宁德时代新能源科技股份有限公司 2024-05-14 CN disclosed
EP-4321505-A1 IONIC COMPOUND AND USE THEREOF, PEROVSKITE PRECURSOR SOLUTION, PEROVSKITE MATERIAL, SOLAR CELL, AND ELECTRICAL DEVICE Contemporary Amperex Technology Co., Ltd. (CN) 2024-02-14 EP disclosed
WO-2023240629-A1 IONIC COMPOUND AND USE THEREOF, PEROVSKITE PRECURSOR SOLUTION, PEROVSKITE MATERIAL, SOLAR CELL, AND ELECTRICAL DEVICE 宁德时代新能源科技股份有限公司 2023-12-21 WO disclosed
EP-4234566-A1 MODIFIED NUCLEOSIDE OR NUCLEOTIDE BGI Shenzhen (CN) 2023-08-30 EP disclosed
WO-2022083686-A1 MODIFIED NUCLEOSIDE OR NUCLEOTIDE 深圳华大生命科学研究院 2022-04-28 WO disclosed
US-9780310-B2 Heterocyclic compound for organic electroluminescent device and its application TOSOH CORPORATION (JP) 2017-10-03 US disclosed
US-9780310-B2 Heterocyclic compound for organic electroluminescent device and its application TOSOH CORPORATION (JP) 2017-10-03 US disclosed
US-20160056388-A1 HETEROCYCLIC COMPOUND FOR ORGANIC ELECTROLUMINESCENT DEVICE AND ITS APPLICATION TOSOH CORPORATION (JP) 2016-02-25 US disclosed
US-20160056388-A1 HETEROCYCLIC COMPOUND FOR ORGANIC ELECTROLUMINESCENT DEVICE AND ITS APPLICATION TOSOH CORPORATION (JP) 2016-02-25 US disclosed
US-20140155384-A1 COMPOUNDS AND METHODS OF TREATING DIABETES MEDIVATION TECHNOLOGIES, INC. (US) 2014-06-05 US disclosed
WO-2013121439-A2 PROCESS FOR GARENOXACIN MESYLATE GLENMARK GENERICS LIMITED (IN) 2013-08-22 WO disclosed
EP-0885186-A1 AMINO ACID DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THESE COMPOUNDS AND PROCESSES FOR PREPARING THEM Dr. Karl Thomae GmbH (DE) 1998-12-23 EP disclosed
WO-1997019911-A1 AMINO ACID DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THESE COMPOUNDS AND PROCESSES FOR PREPARING THEM DR. KARL THOMAE GMBH (DE) 1997-06-05 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160056388-A1 HETEROCYCLIC COMPOUND FOR ORGANIC ELECTROLUMINESCENT DEVICE AND ITS APPLICATION AOC2, AZI2, KCNH2 HTR5A 554/4885BRD4 116/4885CCL2 2953/4885
US-20240224789-A1 IONIC COMPOUND AND APPLICATION THEREOF, PEROVSKITE PRECURSOR SOLUTION, PEROVSKITE MATERIAL, SOLAR CELL, AND ELECTRIC APPARATUS HCN2, HCN1, PIEZO1 HTR5A 4624/4885BRD4 1144/4885CCL2 2805/4885
US-20140155384-A1 COMPOUNDS AND METHODS OF TREATING DIABETES ADRB2, ADRA2C, ADRA2B HTR5A 18/4885BRD4 522/4885CCL2 2103/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.