Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 5/20 | 0.35 |
| ▸ | CA1 | P00915 | 4/20 | 0.34 |
| ▸ | CA2 | P00918 | 4/20 | 0.34 |
| ▸ | CA4 | P22748 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | IKBKB | O14920 | 2/20 | 0.34 |
| ▸ | CHUK | O15111 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | CRHBP | P24387 | 1/20 | 0.34 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | DHODH | Q02127 | 1/20 | 0.32 |
| ▸ | MALT1 | Q9UDY8 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Propionic Acid SCHEMBL8698743 | 0.79 | MAPT (0.38) | MAPTCA1CA2CA4ALDH1A1 | |
| SCHEMBL8531518 | 0.69 | CA1 (0.34) | MAPTCA1CA2CA4ALDH1A1 | |
| SCHEMBL8428888 | 0.69 | CA1 (0.37) | MAPTCA1CA2CA4SMN1; SMN2 | |
| Propionic Acid SCHEMBL8534857 | 0.69 | USP28 (0.40) | MAPTCA1CA2ALDH1A1SMN1; SMN2 | |
| Propionic Acid SCHEMBL8535637 | 0.65 | TUBB4A (0.38) | MAPTCA1CA2ALDH1A1KDM4E | |
| SCHEMBL8536202 | 0.65 | FFAR1 (0.35) | MAPTCA1CA2CA4ALDH1A1 | |
| SCHEMBL8537256 | 0.64 | L3MBTL1 (0.40) | MAPTCA1CA2CA4ALDH1A1 | |
| SCHEMBL8698661 | 0.64 | KDM4E (0.38) | MAPTCA1CA2CA4ALDH1A1 | |
| SCHEMBL8501213 | 0.61 | CA12 (0.40) | CA1CA2 | |
| SCHEMBL6777725 | 0.60 | RAB9A (0.50) | MAPTCA1CA2ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5773646-A | INTEGRIN INHIBITORS | G. D. SEARLE & CO. (US) | 1998-06-30 | — | — | US | disclosed |