Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 2/20 | 0.46 |
| ▸ | CPB1 | P15086 | 1/20 | 0.45 |
| ▸ | FAAH | O00519 | 2/20 | 0.44 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.44 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.44 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.44 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.44 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.44 |
| ▸ | ME2 | P23368 | 1/20 | 0.43 |
| ▸ | ME1 | P48163 | 1/20 | 0.43 |
| ▸ | ME3 | Q16798 | 1/20 | 0.43 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.43 |
| ▸ | C3AR1 | Q16581 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8545661 | 0.89 | GRIN2B (0.46) | TBXAS1CPB1FAAHCYP19A1CYP11B1 | |
| SCHEMBL8540312 | 0.89 | GRIN2B (0.55) | TBXAS1CPB1FAAHGRIN2B | |
| SCHEMBL8540305 | 0.87 | FKBP1A (0.52) | CPB1CYP19A1ME2ME1ME3 | |
| SCHEMBL8540293 | 0.87 | CPB1 (0.44) | TBXAS1CPB1FAAHGRIN2BCYP2D6 | |
| SCHEMBL9031263 | 0.83 | F10 (0.52) | CPB1FAAHGRIN2BC3AR1MEN1 | |
| SCHEMBL8541116 | 0.83 | FAAH (0.57) | TBXAS1CPB1FAAHGRIN2B | |
| SCHEMBL8538696 | 0.83 | FAAH (0.50) | TBXAS1CPB1FAAHGRIN2BMEN1 | |
| SCHEMBL8695119 | 0.82 | L3MBTL1 (0.53) | CYP2A6CYP19A1CYP11B1CYP11B2CYP2B6 | |
| SCHEMBL8544284 | 0.80 | CYP19A1 (0.49) | TBXAS1CYP2A6CYP19A1CYP11B1CYP11B2 | |
| SCHEMBL9031024 | 0.80 | PKM (0.53) | CPB1FAAHGRIN2BC3AR1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0705258-B1 | AZOLYL-CYCLIC AMINE DERIVATIVES WITH IMMUNOMODULATORY ACTIVITY | KNOLL AG (DE) | 1998-12-30 | — | — | EP | disclosed |
| US-5741800-A | ANTIINFLAMMATORY AGENT, ANTIALLERGENS | KNOLL AKTIENGESELLACHAFT (DE) | 1998-04-21 | — | — | US | disclosed |
| WO-1995000507-A1 | AZOLYL-CYCLIC AMINE DERIVATIVES WITH IMMUNOMODULATORY ACTIVITY | KNOLL AG (DE) | 1995-01-05 | — | — | WO | disclosed |