SCHEMBL854425

SCHEMBL854425

O=C(O)CCOc1ccc(CO)cc1

nearest known ligand 0.65

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.65
FFAR1 O14842 4/20 0.57
LMNA P02545 1/20 0.57
MMP2 P08253 1/20 0.56
LTA4H P09960 6/20 0.50
TSHR P16473 1/20 0.49
FFAR4 Q5NUL3 1/20 0.49
S1PR1 P21453 2/20 0.48
S1PR3 Q99500 1/20 0.48
PPARA Q07869 2/20 0.47
PPARG P37231 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2891962 0.91 FFAR1 (0.58) L3MBTL1FFAR1LMNALTA4HFFAR4
SCHEMBL2710391 0.89 PPARA (0.61) L3MBTL1FFAR1LMNALTA4HS1PR1
SCHEMBL12117110 0.86 L3MBTL1 (0.67) L3MBTL1FFAR1LMNAMMP2LTA4H
SCHEMBL8277617 0.83 L3MBTL1 (0.68) L3MBTL1FFAR1LMNAMMP2LTA4H
SCHEMBL928209 0.83 L3MBTL1 (0.62) L3MBTL1FFAR1LMNAMMP2LTA4H
SCHEMBL11649743 0.81 HRH3 (0.56) LMNALTA4HTSHRPPARAPPARG
SCHEMBL4842616 0.80 FFAR1 (0.61) L3MBTL1FFAR1LMNAMMP2FFAR4
SCHEMBL11949155 0.80 L3MBTL1 (0.76) L3MBTL1FFAR1LMNAMMP2LTA4H
SCHEMBL2468006 0.80 L3MBTL1 (0.69) L3MBTL1FFAR1LMNAMMP2LTA4H
SCHEMBL166364 0.80 ALOX15 (0.63) FFAR1LTA4HTSHRPPARAPPARG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 206 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0929567-B1 SOLID-PHASE PEPTIDE SYNTHESIS ZEALAND PHARMA AS (DK) 2005-03-02 EP claimed
EP-1018526-B1 Process for preparing polyurethane foam GEN ELECTRIC (US) 2004-10-20 EP claimed
US-6664305-B2 Chromatography material and a process of manufacturing that material BIA SEPARATIONS D.O.O. (SI) 2003-12-16 US claimed
US-6660781-B1 Reaction product of tertiary amine and phenoxy acid generates a delayed action catalyst to delay the onset of a reaction between said polyisocyanate, water, and organic polyol WITCO CORPORATION 2003-12-09 US claimed
US-20030125204-A1 Chromatography material and a process of manufacturing that material BIA SEPARATIONS D.O.O. (SI) 2003-07-03 US claimed
EP-1294480-A1 A CHROMATOGRAPHY MATERIAL AND A PROCESS OF MANUFACTURING THAT MATERIAL Bia Separations D.O.O. (SI) 2003-03-26 EP claimed
WO-2002000337-A1 A CHROMATOGRAPHY MATERIAL AND A PROCESS OF MANUFACTURING THAT MATERIAL BIA SEPARATIONS D.O.O. (SI) 2002-01-03 WO claimed
EP-1018526-A1 Process for preparing polyurethane foam CK WITCO CORPORATION (US) 2000-07-12 EP claimed
EP-0929567-A1 IMPROVED SOLID-PHASE PEPTIDE SYNTHESIS AND AGENT FOR USE IN SUCH SYNTHESIS Zealand Pharmaceuticals A/S (DK) 1999-07-21 EP claimed
US-5877214-A Polyaryl-poly(ethylene glycol) supports for solution-phase combinatorial synthesis MERCK & CO., INC. (US) 1999-03-02 US claimed
US-5858534-A FOR SOLID PHASE SYNTHESIS; POLYSTYRENE COATED METAL OXIDE PARTICLES DISPERSED IN POLYSTYRENE MATRIX SOLID PHASE SCIENCES CORP. (US) 1999-01-12 US claimed
WO-1998011125-A1 IMPROVED SOLID-PHASE PEPTIDE SYNTHESIS AND AGENT FOR USE IN SUCH SYNTHESIS ZEALAND PHARMACEUTICALS A/S (DK) 1998-03-19 WO claimed
EP-0608779-A1 Apparatus for peptide synthesis SHIMADZU CORPORATION (JP) 1994-08-03 EP claimed
US-12492225-B2 Melanocyte-regulating peptides IDP DISCOVERY PHARMA, S.L. (ES) 2025-12-09 US disclosed
EP-4572795-A2 METHODS AND COMPOSITIONS FOR TREATING CANCER WITH CANCER-BINDING ADJUVANTS The University of Chicago (US) 2025-06-25 EP disclosed
US-20250114441-A1 POLYMERIC VACCINE FOR OPIOID ADDICTION THE JOHNS HOPKINS UNVERSITY 2025-04-10 US disclosed
US-5877214-A Polyaryl-poly(ethylene glycol) supports for solution-phase combinatorial synthesis MERCK & CO., INC. (US) 1999-03-02 US disclosed
US-5858534-A FOR SOLID PHASE SYNTHESIS; POLYSTYRENE COATED METAL OXIDE PARTICLES DISPERSED IN POLYSTYRENE MATRIX SOLID PHASE SCIENCES CORP. (US) 1999-01-12 US disclosed
WO-1998011126-A1 PEPTIDE PRODRUGS CONTAINING AN ALPHA-HYDROXYACID LINKER ZEALAND PHARMACEUTICALS A/S (DK) 1998-03-19 WO disclosed
US-5601992-A DETECTING INTERACTION BETWEEN PEPTIDE AND TARGET BY PLACING TARGET INTO CONTAINER, OVERLAYING WITH SUBSTRATE, APPLYING BEADS TO SUBSTRATE, EACH BEAD HAVING ASSOCIATED THEREWITH COPIES OF A SINGLE PEPTIDE, ALLOWING DIFFUSION, REACTION BUNSEN RUSH LABORATORIES, INC. (US) 1997-02-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12492225-B2 Melanocyte-regulating peptides MC1R, MITF, MCHR1 L3MBTL1 132/4885FFAR1 4602/4885LMNA 4620/4885
US-20250114441-A1 POLYMERIC VACCINE FOR OPIOID ADDICTION OPRM1, OPRK1, OPRL1 L3MBTL1 1349/4885FFAR1 490/4885LMNA 4868/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.