SCHEMBL1278656

SCHEMBL1278656

Cc1ccc(S(=O)(=O)n2c3ccccc3c3cc(I)ccc32)cc1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTR6 P50406 5/20 0.53
PSEN1 P49768 2/20 0.53
PSEN2 P49810 2/20 0.53
APH1B Q8WW43 2/20 0.53
NCSTN Q92542 2/20 0.53
APH1A Q96BI3 2/20 0.53
PSENEN Q9NZ42 2/20 0.53
AGTR1 P30556 3/20 0.50
ALDH3A1 P30838 2/20 0.48
NOD1 Q9Y239 2/20 0.48
GAA P10253 2/20 0.48
L3MBTL1 Q9Y468 2/20 0.48
HTT P42858 2/20 0.48
ALDH1A1 P00352 2/20 0.48
POLB P06746 1/20 0.48
SMN1; SMN2 Q16637 1/20 0.48
PCSK9 Q8NBP7 1/20 0.46
CXCL8 P10145 1/20 0.46
NOD2 Q9HC29 1/20 0.46
KDM4E B2RXH2 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31621789 0.93 LMNA (0.45) HTR6PSEN1PSEN2APH1BNCSTN
SCHEMBL16605721 0.93 LMNA (0.45) HTR6PSEN1PSEN2APH1BNCSTN
SCHEMBL22916411 0.90 LMNA (0.43) HTR6PSEN1PSEN2APH1BNCSTN
SCHEMBL18713502 0.88 HTR6 (0.58) HTR6PSEN1PSEN2APH1BNCSTN
SCHEMBL9901345 0.87 PSEN1 (0.62) HTR6PSEN1PSEN2APH1BNCSTN
SCHEMBL17297375 0.87 HTR6 (0.67) HTR6PSEN1PSEN2APH1BNCSTN
SCHEMBL29357508 0.87 HTR6 (0.67) HTR6PSEN1PSEN2APH1BNCSTN
SCHEMBL8545209 0.83 HTR6 (0.53) HTR6PSEN1PSEN2APH1BNCSTN
SCHEMBL1278376 0.82 HTR6 (0.52) HTR6PSEN1PSEN2APH1BNCSTN
SCHEMBL16685446 0.82 HTR6 (0.52) HTR6PSEN1PSEN2APH1BNCSTN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 107 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12414463-B2 Condensed cyclic compound and organic light-emitting device including the same SAMSUNG SDI CO., LTD. (KR) 2025-09-09 US disclosed
US-11744152-B2 Benzimidazo[1,2-a]benzimidazole derivatives for electronic applications UDC IRELAND LIMITED (IE) 2023-08-29 US disclosed
US-11744152-B2 Benzimidazo[1,2-a]benzimidazole derivatives for electronic applications UDC IRELAND LIMITED (IE) 2023-08-29 US disclosed
US-11744152-B2 Benzimidazo[1,2-a]benzimidazole derivatives for electronic applications UDC IRELAND LIMITED (IE) 2023-08-29 US disclosed
EP-3356369-B1 BENZIMIDAZOLO[1,2-A]BENZIMIDAZOLE CARRYING TRIAZINE GROUPS FOR ORGANIC LIGHT EMITTING DIODES IDEMITSU KOSAN CO (JP) 2022-05-04 EP disclosed
EP-3356369-B1 BENZIMIDAZOLO[1,2-A]BENZIMIDAZOLE CARRYING TRIAZINE GROUPS FOR ORGANIC LIGHT EMITTING DIODES IDEMITSU KOSAN CO (JP) 2022-05-04 EP disclosed
US-11174258-B2 Benzimidazolo[1,2-a]benzimidazole derivatives for organic light emitting diodes IDEMITSU KOSAN CO., LTD. (JP) 2021-11-16 US disclosed
EP-3356368-B1 BENZIMIDAZOLO[1,2-A]BENZIMIDAZOLE CARRYING BENZIMIDAZOLO[1,2-A]BENZIMIDAZOLYL GROUPS, CARBAZOLYL GROUPS, BENZOFURANE GROUPS OR BENZOTHIOPHENE GROUPS FOR ORGANIC LIGHT EMITTING DIODES IDEMITSU KOSAN CO (JP) 2021-07-21 EP disclosed
EP-3356368-B1 BENZIMIDAZOLO[1,2-A]BENZIMIDAZOLE CARRYING BENZIMIDAZOLO[1,2-A]BENZIMIDAZOLYL GROUPS, CARBAZOLYL GROUPS, BENZOFURANE GROUPS OR BENZOTHIOPHENE GROUPS FOR ORGANIC LIGHT EMITTING DIODES IDEMITSU KOSAN CO (JP) 2021-07-21 EP disclosed
US-20210083200-A1 Benzimidazo[1,2-a]Benzimidazole Derivatives for Electronic Applications UDC IRELAND LTD (IE) 2021-03-18 US disclosed
US-8221905-B2 Carbazole-containing materials in phosphorescent light emitting diodes UNIVERSAL DISPLAY CORPORATION (US) 2012-07-17 US disclosed
US-20120086329-A1 Novel 3, 9-Linked Oliogocarbazole-Based Hosts, Containing DBT and DBF Fragments, Separated by Aromatic Spacers Universal Disolay Corporation (US) 2012-04-12 US disclosed
US-20120086329-A1 Novel 3, 9-Linked Oliogocarbazole-Based Hosts, Containing DBT and DBF Fragments, Separated by Aromatic Spacers Universal Disolay Corporation (US) 2012-04-12 US disclosed
US-20120086329-A1 Novel 3, 9-Linked Oliogocarbazole-Based Hosts, Containing DBT and DBF Fragments, Separated by Aromatic Spacers Universal Disolay Corporation (US) 2012-04-12 US disclosed
WO-2012048266-A1 NOVEL 3, 9-LINKED OLIGOCARBAZOLE-BASED HOSTS, CONTAINING DBT AND DBR FRAGMENTS, SEPARATED BY AROMATIC SPACERS UNIVERSAL DISPLAY CORPORATION (US) 2012-04-12 WO disclosed
WO-2012048266-A1 NOVEL 3, 9-LINKED OLIGOCARBAZOLE-BASED HOSTS, CONTAINING DBT AND DBR FRAGMENTS, SEPARATED BY AROMATIC SPACERS UNIVERSAL DISPLAY CORPORATION (US) 2012-04-12 WO disclosed
EP-2240446-A2 CARBAZOLE-CONTAINING MATERIALS IN PHOSPHORESCENT LIGHT EMITTING DIODES Universal Display Corporation (US) 2010-10-20 EP disclosed
WO-2009086028-A2 CARBAZOLE-CONTAINING MATERIALS IN PHOSPHORESCENT LIGHT EMITTING DIODES UNIVERSAL DISPLAY CORPORATION (US) 2009-07-09 WO disclosed
US-20090153034-A1 CARBAZOLE-CONTAINING MATERIALS IN PHOSPHORESCENT LIGHT EMITTINIG DIODES UNIVERSAL DISPLAY CORPORATION (US) 2009-06-18 US disclosed
US-20090134784-A1 CARBAZOLE-CONTAINING MATERIALS IN PHOSPHORESCENT LIGHT EMITTING DIODES UNIVERSAL DISPLAY CORPORATION (US) 2009-05-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210083200-A1 Benzimidazo[1,2-a]Benzimidazole Derivatives for Electronic Applications PAICS, EIF4A1, ECI1 HTR6 3873/4885PSEN1 3024/4885PSEN2 2806/4885
US-20120086329-A1 Novel 3, 9-Linked Oliogocarbazole-Based Hosts, Containing DBT and DBF Fragments, Separated by Aromatic Spacers DBF4, OGFOD1, DDT HTR6 4444/4885PSEN1 3204/4885PSEN2 2979/4885
US-12414463-B2 Condensed cyclic compound and organic light-emitting device including the same CRY1, CRY2, CCNE2 HTR6 3696/4885PSEN1 1306/4885PSEN2 1108/4885
US-11174258-B2 Benzimidazolo[1,2-a]benzimidazole derivatives for organic light emitting diodes KCNH2, KCNH3, KCNJ2 HTR6 1923/4885PSEN1 4550/4885PSEN2 4158/4885
US-20090134784-A1 CARBAZOLE-CONTAINING MATERIALS IN PHOSPHORESCENT LIGHT EMITTING DIODES OXA1L, PAICS, ORC3 HTR6 3769/4885PSEN1 2622/4885PSEN2 2918/4885
US-20090153034-A1 CARBAZOLE-CONTAINING MATERIALS IN PHOSPHORESCENT LIGHT EMITTINIG DIODES PAICS, CYBA, OXA1L HTR6 4367/4885PSEN1 2600/4885PSEN2 2946/4885
US-11744152-B2 Benzimidazo[1,2-a]benzimidazole derivatives for electronic applications PAICS, EIF4A1, ECI1 HTR6 3873/4885PSEN1 3024/4885PSEN2 2806/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.