Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VCAM1 | P19320 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 8/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | MITF | O75030 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 5/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.42 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.42 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.42 |
| ▸ | ABL1 | P00519 | 5/20 | 0.41 |
| ▸ | BCR | P11274 | 5/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8552324 | 0.85 | MAPT (0.48) | VCAM1MAPTSMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL9408933 | 0.85 | PYGL (0.50) | LMNAALDH1A1NPC1MAPK1RAB9A | |
| SCHEMBL8553499 | 0.82 | TGM2 (0.48) | MAPTSMN1; SMN2LMNAALDH1A1MAPK1 | |
| SCHEMBL8549387 | 0.80 | DPEP1 (0.42) | MEN1KMT2A | |
| SCHEMBL8549459 | 0.78 | PYGL (0.52) | — | |
| SCHEMBL8552907 | 0.77 | ALDH1A1 (0.47) | SMN1; SMN2ALDH1A1KDM4EKMT2ANPSR1 | |
| SCHEMBL8551077 | 0.76 | RAB9A (0.37) | MAPTALDH1A1MAPK1RAB9AGAA | |
| SCHEMBL8545460 | 0.76 | ALDH1A1 (0.34) | MAPTSMN1; SMN2ALDH1A1NPC1MAPK1 | |
| SCHEMBL8152002 | 0.74 | MAPT (0.42) | VCAM1MAPTSMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL8547481 | 0.74 | TGM2 (0.43) | MAPTSMN1; SMN2LMNAALDH1A1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0611786-B1 | Orientation layer for liquid crystals | ROLIC AG (CH) | 1999-04-14 | — | — | EP | disclosed |
| EP-0611786-A1 | Orientation layer for liquid crystals | F. HOFFMANN-LA ROCHE AG (CH) | 1994-08-24 | — | — | EP | disclosed |