Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | TGM2 | P21980 | 1/20 | 0.38 |
| ▸ | PLAAT3 | P53816 | 1/20 | 0.38 |
| ▸ | PLAAT5 | Q96KN8 | 1/20 | 0.38 |
| ▸ | PLAAT2 | Q9NWW9 | 1/20 | 0.38 |
| ▸ | PLAAT4 | Q9UL19 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8551077 | 0.87 | RAB9A (0.37) | ALDH1A1HPGDTAAR1NLRP3TGM2 | |
| SCHEMBL8551790 | 0.85 | MAPT (0.39) | KMT2AAKR1C3CYP2C9TGM2FBP1 | |
| SCHEMBL9408933 | 0.84 | PYGL (0.50) | ALDH1A1HPGDPOLBPLAAT3PLAAT5 | |
| SCHEMBL8549387 | 0.83 | DPEP1 (0.42) | KMT2AEGFR | |
| SCHEMBL8555352 | 0.83 | NLRP3 (0.46) | ALDH1A1HPGDTAAR1CYP1A2CYP2C19 | |
| SCHEMBL8545460 | 0.81 | ALDH1A1 (0.34) | ALDH1A1KMT2ASMN1; SMN2TGM2 | |
| SCHEMBL8553931 | 0.78 | DPEP1 (0.42) | ALDH1A1HPGDTGM2EGFRMAOA | |
| SCHEMBL11340474 | 0.77 | AKR1C3 (0.48) | ALDH1A1HPGDCYP1A2KMT2AAKR1C3 | |
| SCHEMBL11340472 | 0.77 | AKR1C3 (0.48) | ALDH1A1HPGDCYP1A2KMT2AAKR1C3 | |
| SCHEMBL8549538 | 0.77 | GRIK1 (0.46) | ALDH1A1TAAR1CYP1A2CYP2C19NLRP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0611786-B1 | Orientation layer for liquid crystals | ROLIC AG (CH) | 1999-04-14 | — | — | EP | disclosed |
| EP-0611786-A1 | Orientation layer for liquid crystals | F. HOFFMANN-LA ROCHE AG (CH) | 1994-08-24 | — | — | EP | disclosed |