Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGM2 | P21980 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 11/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 4/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | APEX1 | P27695 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | FBP1 | P09467 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.40 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8547323 | 0.83 | MAPT (0.42) | MAPTALDH1A1MEN1KMT2AAPEX1 | |
| SCHEMBL6915911 | 0.82 | FBP1 (0.53) | MAPTALDH1A1MEN1KMT2ATDP1 | |
| SCHEMBL8551807 | 0.82 | TGM2 (0.43) | TGM2MAPTALDH1A1MEN1KMT2A | |
| SCHEMBL8547481 | 0.82 | TGM2 (0.43) | TGM2MAPTALDH1A1MEN1KMT2A | |
| SCHEMBL8546512 | 0.82 | VCAM1 (0.44) | MAPTALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL8549416 | 0.79 | TGM2 (0.47) | TGM2LMNASMN1; SMN2 | |
| SCHEMBL8546509 | 0.79 | TGM2 (0.47) | TGM2MAPTALDH1A1MEN1KMT2A | |
| SCHEMBL8550291 | 0.79 | ALDH1A1 (0.39) | TGM2MAPTALDH1A1MEN1KMT2A | |
| SCHEMBL8550858 | 0.78 | ALDH1A1 (0.47) | TGM2MAPTALDH1A1MEN1KMT2A | |
| SCHEMBL8555056 | 0.78 | THRB (0.43) | TGM2ALDH1A1SMN1; SMN2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0611786-B1 | Orientation layer for liquid crystals | ROLIC AG (CH) | 1999-04-14 | — | — | EP | disclosed |
| EP-0611786-A1 | Orientation layer for liquid crystals | F. HOFFMANN-LA ROCHE AG (CH) | 1994-08-24 | — | — | EP | disclosed |