Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.42 |
| ▸ | MEN1 | O00255 | 5/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.41 |
| ▸ | LMNA | P02545 | 4/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | APEX1 | P27695 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | FBP1 | P09467 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8554180 | 0.86 | GLO1 (0.51) | MAPTMEN1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL8551274 | 0.84 | PLAAT3 (0.41) | MEN1KMT2ALMNASMN1; SMN2HTT | |
| SCHEMBL8552707 | 0.83 | ALDH1A1 (0.52) | LMNASMN1; SMN2HTTALDH1A1KDM4E | |
| SCHEMBL8551386 | 0.83 | MAPT (0.40) | MAPTMEN1KMT2ASMN1; SMN2HTT | |
| SCHEMBL8553499 | 0.83 | TGM2 (0.48) | MAPTMEN1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL8551925 | 0.83 | GRIK1 (0.46) | SMN1; SMN2HTTALDH1A1NPC1RAB9A | |
| SCHEMBL8550399 | 0.83 | ALDH1A1 (0.41) | MAPTMEN1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL8552324 | 0.82 | MAPT (0.48) | MAPTMEN1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL8548352 | 0.81 | SMN1; SMN2 (0.42) | MAPTMEN1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL8550978 | 0.81 | MAPT (0.46) | MAPTMEN1KMT2ALMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0611786-B1 | Orientation layer for liquid crystals | ROLIC AG (CH) | 1999-04-14 | — | — | EP | disclosed |
| EP-0611786-A1 | Orientation layer for liquid crystals | F. HOFFMANN-LA ROCHE AG (CH) | 1994-08-24 | — | — | EP | disclosed |