Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 6/20 | 0.45 |
| ▸ | CHRNA10 | Q9GZZ6 | 1/20 | 0.45 |
| ▸ | CHRNA9 | Q9UGM1 | 1/20 | 0.45 |
| ▸ | HDAC3 | O15379 | 5/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 5/20 | 0.41 |
| ▸ | PRKD1 | Q15139 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | DRD3 | P35462 | 1/20 | 0.38 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8549102 | 0.90 | SMN1; SMN2 (0.39) | HDAC3HDAC8MAPTLMNAALDH1A1 | |
| SCHEMBL8551580 | 0.88 | ALDH1A1 (0.38) | HDAC3HDAC8MAPTLMNAALDH1A1 | |
| SCHEMBL8627748 | 0.83 | MEN1 (0.45) | MAPTLMNAALDH1A1SMN1; SMN2DRD2 | |
| SCHEMBL8553947 | 0.80 | AKR1C3 (0.41) | MAPTLMNAALDH1A1SMN1; SMN2DRD2 | |
| SCHEMBL8550138 | 0.78 | DRD4 (0.44) | NAMPTCHRNA10CHRNA9HDAC3HDAC8 | |
| SCHEMBL8548777 | 0.78 | HTR1D (0.54) | DRD2 | |
| SCHEMBL8550457 | 0.77 | HTR1A (0.51) | MAPTDRD2DRD3 | |
| SCHEMBL8549848 | 0.76 | DRD2 (0.43) | MAPTLMNADRD2PRMT5TP53 | |
| SCHEMBL8553219 | 0.76 | HTR1A (0.52) | MAPTDRD2DRD3 | |
| SCHEMBL8552310 | 0.75 | HTR1A (0.48) | MAPTALDH1A1DRD2DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0836599-A1 | 1,6-DISUBSTITUTED ISOCHROMANS FOR TREATMENT OF MIGRAINE HEADACHES | PHARMACIA & UPJOHN COMPANY (US) | 1998-04-22 | — | — | EP | claimed |