Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 4/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | CXCR3 | P49682 | 4/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 3/20 | 0.38 |
| ▸ | DRD3 | P35462 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8627748 | 0.83 | MEN1 (0.45) | LMNASMN1; SMN2MAPTMEN1KMT2A | |
| SCHEMBL8550428 | 0.83 | ALDH1A1 (0.52) | LMNAHTTDRD2DRD3ALDH1A1 | |
| SCHEMBL8549102 | 0.81 | SMN1; SMN2 (0.39) | LMNASMN1; SMN2MAPTMEN1KMT2A | |
| SCHEMBL8550140 | 0.80 | NAMPT (0.45) | LMNASMN1; SMN2MAPTTP53DRD2 | |
| SCHEMBL8551580 | 0.80 | ALDH1A1 (0.38) | LMNASMN1; SMN2MAPTMEN1KMT2A | |
| SCHEMBL8550899 | 0.78 | LMNA (0.37) | AKR1C3LMNASMN1; SMN2MAPTMEN1 | |
| SCHEMBL8549848 | 0.76 | DRD2 (0.43) | LMNAMAPTTP53DRD2 | |
| SCHEMBL8550516 | 0.74 | DRD4 (0.47) | AKR1C3LMNASMN1; SMN2MAPTMEN1 | |
| SCHEMBL8549399 | 0.68 | CCR3 (0.56) | MAPTKMT2ADRD2DRD3DRD4 | |
| SCHEMBL8549874 | 0.66 | MEN1 (0.44) | LMNASMN1; SMN2MAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0836599-A1 | 1,6-DISUBSTITUTED ISOCHROMANS FOR TREATMENT OF MIGRAINE HEADACHES | PHARMACIA & UPJOHN COMPANY (US) | 1998-04-22 | — | — | EP | disclosed |