Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGM2 | P21980 | 3/20 | 0.47 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.41 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.41 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.41 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.41 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.41 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.40 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | DPEP1 | P16444 | 1/20 | 0.40 |
| ▸ | TEAD1 | P28347 | 4/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8551807 | 0.85 | TGM2 (0.43) | TGM2DPEP1LMNASMN1; SMN2 | |
| SCHEMBL8547481 | 0.83 | TGM2 (0.43) | TGM2HDAC3HDAC1HDAC2HDAC10 | |
| SCHEMBL8547353 | 0.82 | PLAAT3 (0.43) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL8545460 | 0.80 | ALDH1A1 (0.34) | TGM2DPEP1SMN1; SMN2 | |
| SCHEMBL8546509 | 0.80 | TGM2 (0.47) | TGM2HDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL8550291 | 0.80 | ALDH1A1 (0.39) | TGM2HDAC2LMNA | |
| SCHEMBL8553499 | 0.79 | TGM2 (0.48) | TGM2LMNASMN1; SMN2 | |
| SCHEMBL8555056 | 0.79 | THRB (0.43) | TGM2PPARGSMN1; SMN2 | |
| SCHEMBL8554406 | 0.78 | ACACB (0.43) | LMNASMN1; SMN2 | |
| SCHEMBL8549680 | 0.77 | TEAD1 (0.40) | TGM2HDAC3HDAC1HDAC2HDAC10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0611786-B1 | Orientation layer for liquid crystals | ROLIC AG (CH) | 1999-04-14 | — | — | EP | disclosed |
| EP-0611786-A1 | Orientation layer for liquid crystals | F. HOFFMANN-LA ROCHE AG (CH) | 1994-08-24 | — | — | EP | disclosed |