Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | TGM2 | P21980 | 1/20 | 0.32 |
| ▸ | DNM1 | Q05193 | 3/20 | 0.32 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.31 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.31 |
| ▸ | PTGES | O14684 | 1/20 | 0.31 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.31 |
| ▸ | PPARG | P37231 | 1/20 | 0.31 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.30 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.30 |
| ▸ | EGFR | P00533 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8550291 | 0.87 | ALDH1A1 (0.39) | ALDH1A1TSHRMAPK1TDP1TGM2 | |
| SCHEMBL8553056 | 0.82 | DNM1 (0.35) | ALDH1A1TSHRMAPK1TDP1GPR35 | |
| SCHEMBL8555909 | 0.81 | EGFR (0.33) | ALDH1A1TSHRMAPK1TDP1GAA | |
| SCHEMBL8547085 | 0.81 | PDCD1 (0.43) | TGM2PDCD1CD274 | |
| SCHEMBL8551077 | 0.80 | RAB9A (0.37) | ALDH1A1TSHRMAPK1TDP1GAA | |
| SCHEMBL8547481 | 0.75 | TGM2 (0.43) | ALDH1A1TSHRMAPK1TDP1TGM2 | |
| SCHEMBL8551807 | 0.75 | TGM2 (0.43) | ALDH1A1TSHRMAPK1TDP1GAA | |
| SCHEMBL9408933 | 0.74 | PYGL (0.50) | ALDH1A1MAPK1 | |
| SCHEMBL8545460 | 0.74 | ALDH1A1 (0.34) | ALDH1A1TSHRMAPK1TDP1GAA | |
| SCHEMBL8552907 | 0.73 | ALDH1A1 (0.47) | ALDH1A1TGM2EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0611786-B1 | Orientation layer for liquid crystals | ROLIC AG (CH) | 1999-04-14 | — | — | EP | disclosed |
| EP-0611786-A1 | Orientation layer for liquid crystals | F. HOFFMANN-LA ROCHE AG (CH) | 1994-08-24 | — | — | EP | disclosed |