Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCKBR | P32239 | 10/20 | 0.45 |
| ▸ | OXTR | P30559 | 2/20 | 0.45 |
| ▸ | CCKAR | P32238 | 4/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8555479 | 0.88 | CCKBR (0.43) | CCKBROXTRCCKARPOLB | |
| SCHEMBL8554316 | 0.86 | OXTR (0.41) | CCKBROXTRCCKARALDH1A1 | |
| SCHEMBL8552734 | 0.85 | POLB (0.44) | CCKBRCCKARPOLBALDH1A1 | |
| SCHEMBL8553890 | 0.83 | CCKBR (0.67) | CCKBRCCKAR | |
| SCHEMBL8597611 | 0.82 | CCKBR (0.57) | CCKBRCCKAR | |
| SCHEMBL8555248 | 0.82 | OXTR (0.41) | CCKBROXTRCCKARPOLB | |
| SCHEMBL8555289 | 0.81 | CCKBR (0.45) | CCKBROXTRCCKAR | |
| SCHEMBL8798046 | 0.76 | SENP1 (0.52) | CCKBRCCKARALDH1A1 | |
| SCHEMBL9573635 | 0.74 | GABRP (0.56) | CCKBROXTRCCKARPOLB | |
| SCHEMBL8552793 | 0.73 | CCKBR (0.48) | CCKBRCCKAR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0672037-B1 | 1,4-BENZODIAZEPINE DERIVATIVES AND THEIR USE AS CCK-MODULATORS | GLAXO GROUP LTD (GB) | 1998-07-08 | — | — | EP | disclosed |
| US-5569654-A | ADMINISTERING AS ANTAGONISTS OF GASTRIN AND CHOLECYSTOKININ | GLAXO GROUP LIMITED (GB) | 1996-10-29 | — | — | US | disclosed |
| EP-0672037-A1 | 1,4-BENZODIAZEPINE DERIVATIVES AND THEIR USE AS CCK-MODULATORS | GLAXO GROUP LIMITED (GB) | 1995-09-20 | — | — | EP | disclosed |
| WO-1994013648-A1 | 1,4-BENZODIAZEPINE DERIVATIVES AND THEIR USE AS CCK-MODULATORS | GLAXO GROUP LIMITED (GB) | 1994-06-23 | — | — | WO | disclosed |