Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.42 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.42 |
| ▸ | TGM2 | P21980 | 6/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.39 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.39 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.39 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.37 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.37 |
| ▸ | PTGES | O14684 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8549538 | 0.85 | GRIK1 (0.46) | ZDHHC20ZDHHC2TGM2HDAC3HDAC4 | |
| SCHEMBL8555056 | 0.82 | THRB (0.43) | ZDHHC20ZDHHC2TGM2GAATBXAS1 | |
| SCHEMBL8549680 | 0.81 | TEAD1 (0.40) | TGM2HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL8547481 | 0.79 | TGM2 (0.43) | ZDHHC20ZDHHC2TGM2HDAC3HDAC4 | |
| SCHEMBL8549459 | 0.79 | PYGL (0.52) | TGM2 | |
| SCHEMBL8550400 | 0.78 | TGM2 (0.38) | ZDHHC20ZDHHC2TGM2HDAC3HDAC4 | |
| SCHEMBL8554406 | 0.77 | ACACB (0.43) | ALOX5EGFRLMNA | |
| SCHEMBL8551807 | 0.76 | TGM2 (0.43) | TGM2GAALMNA | |
| SCHEMBL8548352 | 0.76 | SMN1; SMN2 (0.42) | AKR1C3TBXAS1ALOX5PTGESPPARG | |
| SCHEMBL8546509 | 0.76 | TGM2 (0.47) | TGM2HDAC3HDAC1HDAC2HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0611786-B1 | Orientation layer for liquid crystals | ROLIC AG (CH) | 1999-04-14 | — | — | EP | disclosed |
| EP-0611786-A1 | Orientation layer for liquid crystals | F. HOFFMANN-LA ROCHE AG (CH) | 1994-08-24 | — | — | EP | disclosed |