Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIK1 | P39086 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.40 |
| ▸ | TGM2 | P21980 | 1/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.38 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.38 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.38 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.38 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.38 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8549459 | 0.86 | PYGL (0.52) | TGM2PYGL | |
| SCHEMBL8551267 | 0.85 | ZDHHC20 (0.42) | TGM2HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL8549680 | 0.81 | TEAD1 (0.40) | GRIK1TGM2HDAC3HDAC4HDAC1 | |
| SCHEMBL8547481 | 0.78 | TGM2 (0.43) | MAPTTGM2HDAC3HDAC4HDAC1 | |
| SCHEMBL8551077 | 0.78 | RAB9A (0.37) | GRIK1MAPTNLRP3TGM2TAAR1 | |
| SCHEMBL8551807 | 0.78 | TGM2 (0.43) | MAPTTGM2MEN1KMT2AALDH1A1 | |
| SCHEMBL8550400 | 0.78 | TGM2 (0.38) | TGM2HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL9408933 | 0.78 | PYGL (0.50) | ALDH1A1PYGL | |
| SCHEMBL8549387 | 0.78 | DPEP1 (0.42) | GRIK1MEN1KMT2APYGL | |
| SCHEMBL8552907 | 0.77 | ALDH1A1 (0.47) | CYP1A2NLRP3TGM2CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0611786-B1 | Orientation layer for liquid crystals | ROLIC AG (CH) | 1999-04-14 | — | — | EP | disclosed |
| EP-0611786-A1 | Orientation layer for liquid crystals | F. HOFFMANN-LA ROCHE AG (CH) | 1994-08-24 | — | — | EP | disclosed |