Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGM2 | P21980 | 4/20 | 0.42 |
| ▸ | MAPT | P10636 | 6/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | APEX1 | P27695 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8550858 | 0.79 | ALDH1A1 (0.47) | TGM2MAPTALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL8551386 | 0.79 | MAPT (0.40) | MAPTALDH1A1KDM4ECYP1A2POLB | |
| SCHEMBL8553499 | 0.76 | TGM2 (0.48) | TGM2MAPTALDH1A1KDM4EPOLB | |
| SCHEMBL8158569 | 0.75 | TDP1 (0.43) | MAPTALDH1A1KDM4ECYP1A2POLB | |
| SCHEMBL8547091 | 0.74 | GAA (0.39) | TGM2MAPTKDM4ESMN1; SMN2HTT | |
| SCHEMBL10364150 | 0.73 | RAB9A (0.51) | TGM2ALDH1A1KDM4ECYP1A2POLB | |
| SCHEMBL8547344 | 0.73 | TGM2 (0.38) | TGM2KMT2AGAA | |
| SCHEMBL8157290 | 0.72 | MAPT (0.41) | MAPTALDH1A1KDM4ECYP1A2POLB | |
| SCHEMBL10362336 | 0.71 | RAB9A (0.48) | TGM2MAPTALDH1A1KDM4EPOLB | |
| SCHEMBL8546512 | 0.71 | VCAM1 (0.44) | MAPTALDH1A1KDM4EPOLBTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0611786-B1 | Orientation layer for liquid crystals | ROLIC AG (CH) | 1999-04-14 | — | — | EP | disclosed |
| EP-0611786-A1 | Orientation layer for liquid crystals | F. HOFFMANN-LA ROCHE AG (CH) | 1994-08-24 | — | — | EP | disclosed |