Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 2/20 | 0.41 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.39 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | PTGES | O14684 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | HAT1 | O14929 | 1/20 | 0.36 |
| ▸ | EP300 | Q09472 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.33 |
| ▸ | CASP6 | P55212 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL251645 | 0.89 | ALOX5 (0.43) | ALOX5PDE3BPDE3ASMN1; SMN2LMNA | |
| SCHEMBL8554263 | 0.88 | ALOX5 (0.39) | ALOX5PDE3BPDE3ASMN1; SMN2LMNA | |
| SCHEMBL8551585 | 0.87 | SMN1; SMN2 (0.48) | ALOX5PDE3BPDE3ASMN1; SMN2LMNA | |
| SCHEMBL7707823 | 0.80 | ALOX5 (0.44) | ALOX5PDE3BPDE3ASMN1; SMN2LMNA | |
| SCHEMBL8553605 | 0.78 | ALOX5 (0.48) | ALOX5PDE3BPDE3ASMN1; SMN2LMNA | |
| SCHEMBL6930961 | 0.78 | ALOX5 (0.39) | ALOX5PDE3BPDE3ASMN1; SMN2LMNA | |
| SCHEMBL8555588 | 0.78 | SMN1; SMN2 (0.47) | ALOX5PDE3BPDE3ASMN1; SMN2LMNA | |
| SCHEMBL8554409 | 0.77 | LMNA (0.47) | ALOX5PDE3BPDE3ASMN1; SMN2LMNA | |
| SCHEMBL7424550 | 0.77 | ALOX5 (0.39) | ALOX5PDE3BPDE3ASMN1; SMN2LMNA | |
| SCHEMBL8558633 | 0.73 | ALOX5 (0.40) | ALOX5PDE3BPDE3ASMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0839030-A2 | BIS- HYDRAZONES] | ALTEON, INC. (US) | 1998-05-06 | — | — | EP | disclosed |
| WO-1996021450-A2 | BIS-[HYDRAZONES] | ALTEON INC. (US) | 1996-07-18 | — | — | WO | disclosed |