Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 1/20 | 0.43 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | FBP1 | P09467 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | MITF | O75030 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8550579 | 0.88 | NPC1 (0.35) | NPC1RAB9AALDH1A1SMN1; SMN2RECQL | |
| SCHEMBL8552707 | 0.86 | ALDH1A1 (0.52) | AKR1C3NPC1RAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL8555352 | 0.86 | NLRP3 (0.46) | AKR1C3NPC1RAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL8550399 | 0.85 | ALDH1A1 (0.41) | AKR1C3AKR1C2NPC1RAB9AALDH1A1 | |
| SCHEMBL8554588 | 0.84 | TRPA1 (0.38) | NPC1RAB9AALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL8551790 | 0.83 | MAPT (0.39) | AKR1C3AKR1C2PTGS1MAPTKMT2A | |
| SCHEMBL8547870 | 0.83 | PDCD1 (0.43) | NPC1RAB9AALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL8554180 | 0.82 | GLO1 (0.51) | ALDH1A1SMN1; SMN2MAPTKMT2AFBP1 | |
| SCHEMBL8552779 | 0.81 | DPEP1 (0.41) | NPC1RAB9AALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL8550321 | 0.81 | DPEP1 (0.41) | NPC1RAB9AALDH1A1SMN1; SMN2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0611786-B1 | Orientation layer for liquid crystals | ROLIC AG (CH) | 1999-04-14 | — | — | EP | disclosed |
| EP-0611786-A1 | Orientation layer for liquid crystals | F. HOFFMANN-LA ROCHE AG (CH) | 1994-08-24 | — | — | EP | disclosed |