Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 2/20 | 0.44 |
| ▸ | RXRA | P19793 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | F10 | P00742 | 4/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | RXRB | P28702 | 2/20 | 0.40 |
| ▸ | PPARD | Q03181 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.39 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.39 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.39 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.39 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.39 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.39 |
| ▸ | CETP | P11597 | 1/20 | 0.38 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.38 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8556976 | 0.92 | SCN9A (0.44) | SCN9ARXRARAB9AF10L3MBTL1 | |
| SCHEMBL8556108 | 0.91 | RXRA (0.41) | SCN9ARXRARAB9AF10L3MBTL1 | |
| SCHEMBL8556768 | 0.89 | NR4A2 (0.45) | RXRARXRBCYP3A4NR4A2 | |
| SCHEMBL8556294 | 0.89 | RXRA (0.49) | RXRARAB9AF10NPC1SMN1; SMN2 | |
| SCHEMBL8560532 | 0.88 | RXRA (0.46) | SCN9ARXRAF10RXRBCYP3A4 | |
| SCHEMBL8559961 | 0.87 | RXRA (0.43) | SCN9ARXRAL3MBTL1NPC1MEN1 | |
| SCHEMBL8556320 | 0.86 | GRM2 (0.42) | SCN9ARXRAF10RXRBCYP3A4 | |
| SCHEMBL8560691 | 0.86 | CA1 (0.41) | RXRAL3MBTL1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL8557664 | 0.86 | L3MBTL1 (0.43) | RXRARAB9AL3MBTL1NPC1SMN1; SMN2 | |
| SCHEMBL8561129 | 0.86 | PTGS2 (0.44) | SCN9ARXRARXRBPTGDR2NR4A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5719163-A | ARTHRITIS | G.D. SEARLE & CO. (US) | 1998-02-17 | — | — | US | disclosed |