Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5AP | P20292 | 6/20 | 0.41 |
| ▸ | FEN1 | P39748 | 6/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.40 |
| ▸ | F10 | P00742 | 2/20 | 0.40 |
| ▸ | LDHA | P00338 | 1/20 | 0.36 |
| ▸ | LDHB | P07195 | 1/20 | 0.36 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.34 |
| ▸ | GPR68 | Q15743 | 1/20 | 0.34 |
| ▸ | F2 | P00734 | 1/20 | 0.34 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.34 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.34 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8554948 | 0.92 | PTGS2 (0.42) | ALOX5APFEN1PTGS1PTGS2F10 | |
| SCHEMBL8557215 | 0.91 | PTGS2 (0.42) | ALOX5APFEN1PTGS1PTGS2F10 | |
| SCHEMBL8556992 | 0.91 | PTGS1 (0.40) | ALOX5APFEN1PTGS1PTGS2F10 | |
| SCHEMBL8561414 | 0.88 | PTGS2 (0.47) | ALOX5APFEN1PTGS1PTGS2SCN9A | |
| SCHEMBL8561129 | 0.88 | PTGS2 (0.44) | PTGS1PTGS2SCN9ANR4A2CA12 | |
| SCHEMBL8556529 | 0.88 | RXRA (0.40) | ALOX5APFEN1PTGS1PTGS2F10 | |
| SCHEMBL8555605 | 0.87 | RXRA (0.44) | ALOX5APFEN1PTGS1PTGS2SCN9A | |
| SCHEMBL8556768 | 0.87 | NR4A2 (0.45) | PTGS1PTGS2NR4A2RXRARXRB | |
| SCHEMBL8555226 | 0.86 | RXRA (0.46) | PTGS1PTGS2NR4A2RXRARXRB | |
| SCHEMBL8560516 | 0.86 | FAAH (0.36) | ALOX5APFEN1SCN9ANR4A2CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5719163-A | ARTHRITIS | G.D. SEARLE & CO. (US) | 1998-02-17 | — | — | US | disclosed |