Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR4 | P61073 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CYP2A13 | Q16696 | 5/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7481150 | 0.79 | ALDH1A1 (0.41) | HTTSMN1; SMN2CYP2C9MEN1ALDH1A1 | |
| SCHEMBL8556657 | 0.77 | MEN1 (0.51) | HSD17B10MEN1ALDH1A1KMT2A | |
| SCHEMBL8560517 | 0.76 | CYP2C19 (0.40) | HTTSMN1; SMN2CYP2C9ALOX15HSD17B10 | |
| SCHEMBL8555169 | 0.76 | DRD2 (0.38) | MEN1ALDH1A1KMT2A | |
| SCHEMBL8555562 | 0.76 | DRD4 (0.54) | HTTSMN1; SMN2ALDH1A1KMT2AGAA | |
| SCHEMBL8556503 | 0.75 | SIGMAR1 (0.58) | HSD17B10ALDH1A1KMT2ACYP3A4 | |
| SCHEMBL8559788 | 0.73 | MAPT (0.50) | HTTSMN1; SMN2ALOX15HSD17B10MEN1 | |
| SCHEMBL6270109 | 0.73 | CXCR4 (0.53) | CXCR4HTTHRH3CYP2C9ALOX15 | |
| SCHEMBL8555924 | 0.70 | MAPT (0.53) | HTTHSD17B10MEN1ALDH1A1KMT2A | |
| SCHEMBL8671225 | 0.69 | POLB (0.44) | HTTSMN1; SMN2ALDH1A1KMT2AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0883622-A1 | PROTON PUMP INHIBITOR | APOTEX INC. (CA) | 1998-12-16 | — | — | EP | claimed |
| WO-1997031923-A1 | PROTON PUMP INHIBITOR | APOTEX INC. (CA) | 1997-09-04 | — | — | WO | claimed |
| EP-0883606-A1 | PROCESS FOR SCAVENGING THIOLS | APOTEX INC. (CA) | 1998-12-16 | — | — | EP | disclosed |
| WO-1997031893-A1 | PROCESS FOR SCAVENGING THIOLS | APOTEX INC. (CA) | 1997-09-04 | — | — | WO | disclosed |