Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLK1 | P53350 | 1/20 | 0.35 |
| ▸ | CTSL | P07711 | 5/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | CTSB | P07858 | 1/20 | 0.33 |
| ▸ | CTSS | P25774 | 1/20 | 0.33 |
| ▸ | CTSK | P43235 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | GRM7 | Q14831 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | BACE1 | P56817 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9260996 | 1.00 | PLK1 (0.35) | PLK1CTSLALDH1A1L3MBTL1GAA | |
| SCHEMBL12203627 | 0.79 | ALDH1A1 (0.36) | CTSLALDH1A1SIGMAR1SMN1; SMN2BACE1 | |
| SCHEMBL8558815 | 0.73 | TAAR1 (0.34) | ALDH1A1L3MBTL1GAASIGMAR1GRM7 | |
| SCHEMBL9180894 | 0.73 | TAAR1 (0.34) | ALDH1A1L3MBTL1GAASIGMAR1GRM7 | |
| SCHEMBL8557818 | 0.72 | SIGMAR1 (0.40) | CTSLALDH1A1GAACTSBCTSS | |
| SCHEMBL9515959 | 0.69 | ADRA2A (0.35) | ALDH1A1SIGMAR1SMN1; SMN2BACE1 | |
| SCHEMBL5674636 | 0.69 | OPRM1 (0.53) | ALDH1A1SIGMAR1SMN1; SMN2POLB | |
| Hydrochloric Acid SCHEMBL1394817 | 0.68 | DPP4 (0.35) | ALDH1A1GAA | |
| SCHEMBL31066655 | 0.66 | CTSL (0.39) | CTSLCTSBCTSSCTSKGRM7 | |
| SCHEMBL20741223 | 0.64 | ADRA2A (0.36) | ALDH1A1SIGMAR1BACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0635497-B1 | Benzospiroalkene derivatives, process for their preparation and pharmaceutical compostions containing them | ADIR (FR) | 1998-05-20 | — | — | EP | disclosed |
| EP-0635497-A2 | Benzospiroalkene derivatives, process for their preparation and pharmaceutical compostions containing them | ADIR ET COMPAGNIE (FR) | 1995-01-25 | — | — | EP | disclosed |