Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMPD1 | P17405 | 1/20 | 0.36 |
| ▸ | DUSP10 | Q9Y6W6 | 1/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.34 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.34 |
| ▸ | PORCN | Q9H237 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 3/20 | 0.34 |
| ▸ | RAB9A | P51151 | 3/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.34 |
| ▸ | RELA | Q04206 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8560309 | 0.85 | KCNH2 (0.39) | FFAR1KDM4EMAPTENPP3ENPP1 | |
| SCHEMBL8559969 | 0.81 | PPARD (0.49) | KDM4EMAPTMEN1L3MBTL1NPC1 | |
| SCHEMBL8835183 | 0.78 | PARP10 (0.50) | KDM4ENPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL8557960 | 0.78 | GRM5 (0.41) | SMPD1KMT2AKDM4EMAPTMEN1 | |
| SCHEMBL8557729 | 0.77 | PDE10A (0.43) | FFAR1KMT2AKDM4EMAPTNPC1 | |
| SCHEMBL8834199 | 0.76 | GPBAR1 (0.55) | FFAR1 | |
| SCHEMBL8559981 | 0.76 | PARP10 (0.39) | FFAR1KMT2AKDM4EMEN1NPC1 | |
| SCHEMBL8559028 | 0.76 | PDE10A (0.45) | KMT2AMAPTMEN1NPC1RAB9A | |
| SCHEMBL8557961 | 0.74 | MAPT (0.42) | KMT2AKDM4EMAPTMEN1L3MBTL1 | |
| SCHEMBL8557149 | 0.71 | KMT2A (0.38) | SMPD1DUSP10KMT2AKDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5714488-A | FOR TREATMENT OF ALLERGIC AND INFLAMMATORY DISEASE STATES | ABBOTT LABORATORIES (US) | 1998-02-03 | — | — | US | disclosed |