Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.45 |
| ▸ | LMNA | P02545 | 6/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.45 |
| ▸ | GAA | P10253 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 4/20 | 0.38 |
| ▸ | USP2 | O75604 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9535858 | 0.82 | PKM (0.51) | HSD11B1ALDH1A1LMNANPSR1GAA | |
| Sulfamic Acid Cyclohexyl Ester SCHEMBL9302699 | 0.74 | MAPK1 (0.41) | ALDH1A1LMNANPSR1MEN1HPGD | |
| Cyclamic Acid SCHEMBL8563768 | 0.74 | MAPK1 (0.43) | ALDH1A1LMNAGAAMEN1HPGD | |
| SCHEMBL9564855 | 0.69 | USP2 (0.49) | ALDH1A1LMNAHPGDSMN1; SMN2MAPK1 | |
| SCHEMBL14263834 | 0.68 | TNF (0.57) | ALDH1A1LMNAHPGDSMN1; SMN2PKM | |
| SCHEMBL10797955 | 0.67 | GAA (0.56) | HSD11B1ALDH1A1LMNAGAAMEN1 | |
| SCHEMBL9536864 | 0.67 | KMT2A (0.53) | HSD11B1ALDH1A1LMNANPSR1GAA | |
| SCHEMBL4991751 | 0.66 | LMNA (0.45) | ALDH1A1LMNAMEN1HPGDKMT2A | |
| SCHEMBL8563059 | 0.66 | HPGD (0.42) | ALDH1A1LMNAHPGDTSHRUSP2 | |
| SCHEMBL10798877 | 0.66 | ALDH1A1 (0.57) | ALDH1A1LMNAGAAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0539421-B1 | NOVEL OXAZOLYL DERIVATIVES | JANSSEN PHARMACEUTICA NV (BE) | 1998-09-23 | — | — | EP | disclosed |
| US-5278165-A | Oxazolyl imidazol[4,5-b]pyridin and pyrimidine compounds | JANSSEN PHARMACEUTICA N.V. (BE) | 1994-01-11 | — | — | US | disclosed |
| US-5217980-A | Antiallergens | JANSSEN PHARMACEUTICA N.V. (BE) | 1993-06-08 | — | — | US | disclosed |
| EP-0539421-A1 | NOVEL OXAZOLYL DERIVATIVES | JANSSEN PHARMACEUTICA N.V. (BE) | 1993-05-05 | — | — | EP | disclosed |
| WO-1992001687-A1 | NOVEL OXAZOLYL DERIVATIVES | JANSSEN PHARMACEUTICA N.V. (BE) | 1992-02-06 | — | — | WO | disclosed |