Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.52 |
| ▸ | RAB9A | P51151 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.52 |
| ▸ | NPC1 | O15118 | 2/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
| ▸ | CA9 | Q16790 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | TYR | P14679 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | APP | P05067 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | APEX1 | P27695 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16281925 | 0.93 | RAB9A (0.63) | MAPTRAB9AALDH1A1MAPK1NPC1 | |
| SCHEMBL16281935 | 0.93 | KIF11 (0.50) | MAPTRAB9AALDH1A1MAPK1NPC1 | |
| SCHEMBL16281926 | 0.93 | MAPT (0.47) | MAPTRAB9AALDH1A1MAPK1NPC1 | |
| SCHEMBL21782373 | 0.93 | RAB9A (0.63) | MAPTRAB9AALDH1A1MAPK1NPC1 | |
| SCHEMBL24517623 | 0.87 | ELANE (0.43) | MAPTRAB9AALDH1A1MAPK1NPC1 | |
| SCHEMBL16281923 | 0.87 | APP (0.47) | MAPTRAB9AALDH1A1MAPK1NPC1 | |
| SCHEMBL16281931 | 0.87 | ALDH1A1 (0.42) | MAPTRAB9AALDH1A1MAPK1NPC1 | |
| SCHEMBL22883647 | 0.87 | RAB9A (0.57) | MAPTRAB9AALDH1A1MAPK1NPC1 | |
| SCHEMBL26746 | 0.86 | SLC6A2 (0.44) | MAPTRAB9AALDH1A1MAPK1NPC1 | |
| SCHEMBL16281932 | 0.85 | TRPV1 (0.43) | MAPTRAB9AALDH1A1MAPK1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 108 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230312511-A1 | SELECTIVE D3 DOPAMINE RECEPTOR AGONISTS AND METHODS OF THEIR USE | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL | 2023-10-05 | — | — | US | disclosed |
| US-20230312511-A1 | SELECTIVE D3 DOPAMINE RECEPTOR AGONISTS AND METHODS OF THEIR USE | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL | 2023-10-05 | — | — | US | disclosed |
| US-20230295105-A1 | PIPERIDINEDIONE DERIVATIVES | INNOCURE THERAPEUTICS, INC. (KR) | 2023-09-21 | — | — | US | disclosed |
| US-11753421-B2 | Silylated derivatives of aromatic heterocycles | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2023-09-12 | — | — | US | disclosed |
| US-11753421-B2 | Silylated derivatives of aromatic heterocycles | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2023-09-12 | — | — | US | disclosed |
| US-11673864-B2 | Pyridone amides as modulators of sodium channels | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2023-06-13 | — | — | US | disclosed |
| US-11673864-B2 | Pyridone amides as modulators of sodium channels | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2023-06-13 | — | — | US | disclosed |
| US-20230128688-A1 | DIRECTED CONJUGATION TECHNOLOGIES | KLEO PHARMACEUTICALS, INC. | 2023-04-27 | — | — | US | disclosed |
| EP-3569626-B1 | EPOXY RESIN COMPOSITION | SUMITOMO SEIKA CHEMICALS (JP) | 2023-03-01 | — | — | EP | disclosed |
| US-20220356289-A1 | RESIN COMPOSITION, PREPREG, FILM WITH RESIN, METAL FOIL WITH RESIN, METAL-CLAD LAMINATED BOARD, AND WIRING BOARD | PANASONIC INTELLECTUAL PROPERTY MANAGEMENT CO., LTD. (JP) | 2022-11-10 | — | — | US | disclosed |
| EP-1097158-B1 | LIGANDS FOR METALS AND METAL-CATALYZED PROCESSES | MASSACHUSETTS INST TECHNOLOGY (US) | 2006-01-25 | — | — | EP | disclosed |
| EP-1354887-A1 | Ligands for metals and improved metal-catalyzed processes based thereon | Massachusetts Insitute of Technology (US) | 2003-10-22 | — | — | EP | disclosed |
| EP-1027316-B1 | SYNTHESIS OF ARYL ETHERS, METHODS AND REAGENTS RELATED THERETO | MASSACHUSETTS INST TECHNOLOGY (US) | 2003-05-21 | — | — | EP | disclosed |
| EP-1254884-A2 | Preparation of vinyl ethers from alcohols and alkenes | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2002-11-06 | — | — | EP | disclosed |
| EP-1245553-A2 | Palladium-catalysed synthesis of aryl ethers | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2002-10-02 | — | — | EP | disclosed |
| US-20010008942-A1 | Synthesis of aryl ethers | BUCHWALD STEPHEN L (US) | 2001-07-19 | — | — | US | disclosed |
| EP-1097158-A2 | LIGANDS FOR METALS AND METAL-CATALYZED PROCESSES | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2001-05-09 | — | — | EP | disclosed |
| US-6166226-A | Synthesis of aryl ethers | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2000-12-26 | — | — | US | disclosed |
| WO-2000002887-A2 | LIGANDS FOR METALS AND METAL-CATALYZED PROCESSES | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2000-01-20 | — | — | WO | disclosed |
| US-5847166-A | Synthesis of aryl ethers | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 1998-12-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230128688-A1 | DIRECTED CONJUGATION TECHNOLOGIES | CD2BP2, CD2, CD47 | MAPT 2513/4885RAB9A 1639/4885ALDH1A1 1047/4885 |
| US-20010008942-A1 | Synthesis of aryl ethers | AHR, PAH, PDK1 | MAPT 3843/4885RAB9A 1018/4885ALDH1A1 688/4885 |
| US-20230295105-A1 | PIPERIDINEDIONE DERIVATIVES | CRBN, CUL1, PSMB10 | MAPT 2906/4885RAB9A 2067/4885ALDH1A1 2741/4885 |
| US-11753421-B2 | Silylated derivatives of aromatic heterocycles | KCNH1, KCNH3, HNRNPH3 | MAPT 4150/4885RAB9A 2128/4885ALDH1A1 1686/4885 |
| US-20230312511-A1 | SELECTIVE D3 DOPAMINE RECEPTOR AGONISTS AND METHODS OF THEIR USE | SLC6A3, DRD3, DRD2 | MAPT 429/4885RAB9A 317/4885ALDH1A1 2379/4885 |
| US-11673864-B2 | Pyridone amides as modulators of sodium channels | SCN5A, SCN1A, KCNJ2 | MAPT 2938/4885RAB9A 3216/4885ALDH1A1 1133/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.