Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | HTT | P42858 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | MAOA | P21397 | 2/20 | 0.41 |
| ▸ | MAOB | P27338 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8570726 | 0.83 | PDE4A (0.42) | L3MBTL1LMNAHTTALDH1A1MAPT | |
| SCHEMBL8566460 | 0.78 | HTR1A (0.45) | L3MBTL1LMNAALDH1A1MAPTTSHR | |
| SCHEMBL8565869 | 0.75 | HTR1A (0.67) | HTTCYP1A2CYP3A4KMT2AHTR1A | |
| SCHEMBL9475224 | 0.72 | MAOA (0.64) | L3MBTL1LMNAHTTALDH1A1MAPT | |
| SCHEMBL481976 | 0.72 | MAOA (0.64) | L3MBTL1LMNAHTTALDH1A1MAPT | |
| SCHEMBL9476350 | 0.72 | MAOA (0.64) | L3MBTL1LMNAHTTALDH1A1MAPT | |
| SCHEMBL8570657 | 0.71 | HTR1A (0.50) | L3MBTL1ALDH1A1MAPTHPGDKMT2A | |
| SCHEMBL5246815 | 0.71 | LMNA (0.58) | L3MBTL1LMNAHTTALDH1A1MAPT | |
| SCHEMBL8372101 | 0.71 | L3MBTL1 (0.47) | L3MBTL1LMNAHTTALDH1A1MAPT | |
| SCHEMBL6546581 | 0.70 | MAOA (0.61) | L3MBTL1LMNAHTTALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0826674-A1 | NOVEL PYRIMIDINE DERIVATIVES EFFICACIOUS AS PSYCHOTROPIC DRUG AND PROCESS FOR THE PRODUCTION THEREOF | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1998-03-04 | — | — | EP | disclosed |