Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 4/20 | 0.50 |
| ▸ | DRD2 | P14416 | 4/20 | 0.50 |
| ▸ | DRD4 | P21917 | 3/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | TYMS | P04818 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.39 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | DHFR | P00374 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8564591 | 0.86 | HTR1A (0.64) | HTR1ADRD2DRD4HPGDTYMS | |
| SCHEMBL8564897 | 0.80 | HTR1A (0.49) | HTR1ADRD2DRD4HPGDTYMS | |
| SCHEMBL8564570 | 0.80 | HTR1A (0.82) | HTR1ADRD2DRD4 | |
| SCHEMBL8566460 | 0.79 | HTR1A (0.45) | HTR1ADRD2DRD4HPGDL3MBTL1 | |
| SCHEMBL8569140 | 0.71 | L3MBTL1 (0.46) | HTR1ADRD2DRD4HPGDL3MBTL1 | |
| SCHEMBL10994004 | 0.70 | HTR1A (0.57) | HTR1ADRD2DRD4MAPTPOLB | |
| SCHEMBL8565639 | 0.68 | HTR1A (1.00) | HTR1ADRD2DRD4 | |
| SCHEMBL481976 | 0.66 | MAOA (0.64) | HPGDL3MBTL1MAPTMEN1ALDH1A1 | |
| SCHEMBL9476350 | 0.66 | MAOA (0.64) | HPGDL3MBTL1MAPTMEN1ALDH1A1 | |
| SCHEMBL9475224 | 0.66 | MAOA (0.64) | HPGDL3MBTL1MAPTMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0826674-A1 | NOVEL PYRIMIDINE DERIVATIVES EFFICACIOUS AS PSYCHOTROPIC DRUG AND PROCESS FOR THE PRODUCTION THEREOF | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1998-03-04 | — | — | EP | disclosed |