Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | HTR2A | P28223 | 1/20 | 0.47 |
| ▸ | HTR2C | P28335 | 1/20 | 0.47 |
| ▸ | HTR2B | P41595 | 1/20 | 0.47 |
| ▸ | GPR27 | Q9NS67 | 2/20 | 0.47 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.46 |
| ▸ | KDM1A | O60341 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8574479 | 0.90 | ALDH1A1 (0.52) | LMNAL3MBTL1ALDH1A1GAAHTR2A | |
| SCHEMBL8572431 | 0.89 | LMNA (0.61) | LMNAL3MBTL1ALDH1A1GAAALOX15 | |
| SCHEMBL8574314 | 0.85 | HTR2C (0.60) | ALDH1A1HTR2AHTR2CHTR2BALOX15 | |
| SCHEMBL8573946 | 0.82 | HDAC8 (0.40) | LMNAL3MBTL1ALDH1A1GAAHTR2A | |
| SCHEMBL8567801 | 0.80 | KCNK3 (0.55) | LMNAALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL8604235 | 0.80 | FABP4 (0.37) | HTR6LMNAL3MBTL1ALDH1A1GAA | |
| SCHEMBL8575779 | 0.78 | HSD11B1 (0.46) | ALDH1A1HTR2AHTR2CHTR2BMAPK1 | |
| SCHEMBL8574070 | 0.78 | ALDH1A1 (0.51) | LMNAL3MBTL1ALDH1A1MAPK1HTT | |
| SCHEMBL8567723 | 0.77 | HTR2C (0.62) | ALDH1A1HTR2AHTR2CHTR2BALOX15 | |
| SCHEMBL8569681 | 0.77 | HTR2A (0.56) | ALDH1A1HTR2AHTR2CHTR2BMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5739336-A | SELECTIVE 5-HYDROXYTRYPTAMINE-2C RECEPTOR ANTAGONISTS | SYNTEX (U.S.A.) INC. (US) | 1998-04-14 | — | — | US | disclosed |
| WO-1997000872-A1 | 1,3,8-TRIAZA- AND 3,8-DIAZA-1-OXASPIRO(4,5)DECANE DERIVATIVES | F.HOFFMANN-LA ROCHE AG (CH) | 1997-01-09 | — | — | WO | disclosed |