Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FABP4 | P15090 | 4/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.37 |
| ▸ | HTR6 | P50406 | 1/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 1/20 | 0.34 |
| ▸ | HTR2B | P41595 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | FABP5 | Q01469 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8570504 | 0.80 | HTR6 (0.52) | HTR6HSD11B1MEN1KMT2AALDH1A1 | |
| SCHEMBL8572431 | 0.76 | LMNA (0.61) | HDAC1HDAC8MEN1KMT2AALDH1A1 | |
| SCHEMBL8573946 | 0.75 | HDAC8 (0.40) | FABP4HDAC1HDAC8HSD11B1MEN1 | |
| SCHEMBL8567801 | 0.73 | KCNK3 (0.55) | MEN1KMT2AALDH1A1POLBLMNA | |
| SCHEMBL8574479 | 0.73 | ALDH1A1 (0.52) | MEN1KMT2AALDH1A1LMNAGAA | |
| SCHEMBL8574070 | 0.71 | ALDH1A1 (0.51) | HDAC1HDAC8MEN1KMT2AALDH1A1 | |
| SCHEMBL8569681 | 0.70 | HTR2A (0.56) | HDAC1HDAC8HSD11B1MEN1KMT2A | |
| SCHEMBL8570812 | 0.70 | GRM4 (0.54) | HDAC1HDAC8MEN1KMT2AALDH1A1 | |
| SCHEMBL8572525 | 0.68 | ALDH1A1 (0.56) | HDAC1HDAC8MEN1KMT2AALDH1A1 | |
| SCHEMBL8569833 | 0.68 | HSD11B1 (0.48) | HDAC1HDAC8HSD11B1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5739336-A | SELECTIVE 5-HYDROXYTRYPTAMINE-2C RECEPTOR ANTAGONISTS | SYNTEX (U.S.A.) INC. (US) | 1998-04-14 | — | — | US | disclosed |