Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.42 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.42 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 5/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | CRHBP | P24387 | 1/20 | 0.39 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.39 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.38 |
| ▸ | LCK | P06239 | 2/20 | 0.37 |
| ▸ | MMP2 | P08253 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8668515 | 0.86 | S1PR2 (0.38) | TAS1R3TAS1R1TAS1R2MEN1KMT2A | |
| SCHEMBL8599822 | 0.85 | ALDH1A1 (0.37) | TAS1R3TAS1R1TAS1R2MEN1KMT2A | |
| SCHEMBL8602578 | 0.84 | RAB9A (0.43) | MEN1KMT2AHTTMMP2POLB | |
| SCHEMBL8599596 | 0.84 | LMNA (0.40) | MEN1KMT2ASMN1; SMN2MMP2POLB | |
| SCHEMBL8600718 | 0.82 | PIK3CD (0.42) | MEN1KMT2AHTTSMN1; SMN2CRHBP | |
| SCHEMBL8597312 | 0.81 | TP53 (0.43) | MEN1KMT2AHTTSMN1; SMN2CRHBP | |
| SCHEMBL8597130 | 0.79 | MEN1 (0.38) | MEN1KMT2AHTTSMN1; SMN2CRHBP | |
| Trifluoroacetic Acid SCHEMBL8598750 | 0.78 | CDK4 (0.42) | MEN1KMT2AHTTSMN1; SMN2CRHBP | |
| SCHEMBL8600749 | 0.77 | MEN1 (0.40) | TAS1R3TAS1R1TAS1R2MEN1KMT2A | |
| SCHEMBL8599257 | 0.76 | HSD17B10 (0.43) | TAS1R3TAS1R1TAS1R2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0863881-A1 | BENZIMIDAZOLE DERIVATIVES AND THEIR USE IN THE PREVENTION AND/OR THE TREATMENT OF BONE DISEASES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1998-09-16 | — | — | EP | disclosed |
| WO-1997010219-A1 | BENZIMIDAZOLE DERIVATIVES AND THEIR USE IN THE PREVENTION AND/OR THE TREATMENT OF BONE DISEASES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-03-20 | — | — | WO | disclosed |