Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 7/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | DRD4 | P21917 | 1/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | CCNT1 | O60563 | 2/20 | 0.38 |
| ▸ | CDK9 | P50750 | 2/20 | 0.38 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.38 |
| ▸ | CDK5R1 | Q15078 | 2/20 | 0.38 |
| ▸ | CASK | O14936 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8571701 | 0.84 | TAS1R3 (0.42) | MEN1KMT2AKDM4EHTTALDH1A1 | |
| SCHEMBL8668515 | 0.83 | S1PR2 (0.38) | RAB9AMEN1KMT2ATSHRHTT | |
| SCHEMBL8599596 | 0.80 | LMNA (0.40) | MEN1KMT2ATSHRKDM4EALDH1A1 | |
| SCHEMBL8599822 | 0.78 | ALDH1A1 (0.37) | MEN1KMT2AKDM4ENPC1HTT | |
| SCHEMBL8600749 | 0.71 | MEN1 (0.40) | RAB9AMEN1KMT2ATSHRKDM4E | |
| SCHEMBL9081819 | 0.70 | SMN1; SMN2 (0.44) | RAB9AMEN1KMT2ATSHRKDM4E | |
| SCHEMBL8600307 | 0.70 | TP53 (0.44) | HTTALDH1A1MMP2 | |
| SCHEMBL8599257 | 0.69 | HSD17B10 (0.43) | RAB9AMEN1KMT2ATSHRKDM4E | |
| SCHEMBL8598251 | 0.69 | TYK2 (0.39) | MEN1KMT2AHTTCYP3A4 | |
| SCHEMBL8569083 | 0.69 | MMP2 (0.43) | RAB9AMEN1KMT2ATSHRNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0863881-A1 | BENZIMIDAZOLE DERIVATIVES AND THEIR USE IN THE PREVENTION AND/OR THE TREATMENT OF BONE DISEASES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1998-09-16 | — | — | EP | disclosed |
| WO-1997010219-A1 | BENZIMIDAZOLE DERIVATIVES AND THEIR USE IN THE PREVENTION AND/OR THE TREATMENT OF BONE DISEASES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-03-20 | — | — | WO | disclosed |