Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 4/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MMP2 | P08253 | 1/20 | 0.38 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.37 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.37 |
| ▸ | PTGES | O14684 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8668515 | 0.90 | S1PR2 (0.38) | LMNATSHRMMP2P2RX7MEN1 | |
| SCHEMBL8571701 | 0.84 | TAS1R3 (0.42) | THRBPOLBHPGDMMP2MEN1 | |
| SCHEMBL8599822 | 0.82 | ALDH1A1 (0.37) | POLBMMP2P2RX7MEN1KMT2A | |
| SCHEMBL8602578 | 0.80 | RAB9A (0.43) | POLBHPGDTSHRMMP2MEN1 | |
| SCHEMBL8602955 | 0.78 | MMP2 (0.43) | LMNATSHRMMP2P2RX7MEN1 | |
| SCHEMBL8599275 | 0.77 | TP53 (0.42) | POLBMMP2MEN1KMT2AALDH1A1 | |
| SCHEMBL8600307 | 0.76 | TP53 (0.44) | MMP2ALDH1A1PTGESSMN1; SMN2 | |
| SCHEMBL8602120 | 0.75 | PTGES (0.44) | LMNAPOLBMMP2MEN1KMT2A | |
| SCHEMBL8597757 | 0.73 | L3MBTL1 (0.46) | LMNAMMP2MEN1KMT2AALDH1A1 | |
| SCHEMBL8600749 | 0.73 | MEN1 (0.40) | LMNAPOLBTSHRMMP2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0863881-A1 | BENZIMIDAZOLE DERIVATIVES AND THEIR USE IN THE PREVENTION AND/OR THE TREATMENT OF BONE DISEASES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1998-09-16 | — | — | EP | disclosed |
| WO-1997010219-A1 | BENZIMIDAZOLE DERIVATIVES AND THEIR USE IN THE PREVENTION AND/OR THE TREATMENT OF BONE DISEASES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-03-20 | — | — | WO | disclosed |