Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UGCG | Q16739 | 3/20 | 0.36 |
| ▸ | GAA | P10253 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.33 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8575074 | 0.86 | TSHR (0.35) | GAAALDH1A1LMNATSHRNPSR1 | |
| SCHEMBL8573201 | 0.85 | POLB (0.37) | GAAALDH1A1TSHRNPSR1ADRA1D | |
| SCHEMBL8575341 | 0.81 | ALDH1A1 (0.39) | GAAALDH1A1HPGDLMNAADRA1D | |
| SCHEMBL8579010 | 0.81 | POLB (0.34) | GAAALDH1A1LMNAUSP2POLB | |
| SCHEMBL8577585 | 0.80 | MAPT (0.37) | GAAALDH1A1LMNAKDM4EPOLB | |
| SCHEMBL8575403 | 0.79 | ALDH1A1 (0.41) | GAAALDH1A1LMNAPOLBMAPT | |
| SCHEMBL8574464 | 0.79 | ACHE (0.36) | GAAALDH1A1TSHRPOLBMAPT | |
| SCHEMBL8576596 | 0.79 | CACNA1G (0.39) | GAAALDH1A1TSHRNPSR1POLB | |
| SCHEMBL8572909 | 0.77 | ADRA1D (0.35) | GAAALDH1A1HPGDADRA1DADRA1A | |
| SCHEMBL8574745 | 0.77 | ADRA2A (0.37) | GAAALDH1A1LMNATSHRNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5710152-A | ANTIDIABETIC, ANTILIPEMIC, AND HYPOGLYCEMIC AGENTS; DIETETICS | SS PHARMACEUTICAL CO., LTD. (JP) | 1998-01-20 | — | — | US | disclosed |