Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 5/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.32 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | BRD4 | O60885 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | PPARG | P37231 | 1/20 | 0.30 |
| ▸ | PPARD | Q03181 | 1/20 | 0.30 |
| ▸ | PPARA | Q07869 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8577585 | 0.90 | MAPT (0.37) | POLBMAPTTP53THRBGAA | |
| SCHEMBL8575074 | 0.90 | TSHR (0.35) | POLBGAAALDH1A1ACHELMNA | |
| SCHEMBL8573201 | 0.88 | POLB (0.37) | POLBMAPTTP53THRBGAA | |
| SCHEMBL8574464 | 0.88 | ACHE (0.36) | POLBMAPTTP53THRBGAA | |
| SCHEMBL8575403 | 0.88 | ALDH1A1 (0.41) | POLBMAPTTP53THRBGAA | |
| SCHEMBL8576804 | 0.85 | ALDH1A1 (0.38) | POLBMAPTTP53THRBGAA | |
| SCHEMBL8572909 | 0.85 | ADRA1D (0.35) | POLBMAPTTHRBGAAALDH1A1 | |
| SCHEMBL8572953 | 0.84 | CASP1 (0.46) | MAPTALDH1A1ACHELMNA | |
| SCHEMBL8573630 | 0.83 | ALDH1A1 (0.40) | POLBMAPTTP53THRBGAA | |
| SCHEMBL8579006 | 0.81 | LMNA (0.32) | LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5710152-A | ANTIDIABETIC, ANTILIPEMIC, AND HYPOGLYCEMIC AGENTS; DIETETICS | SS PHARMACEUTICAL CO., LTD. (JP) | 1998-01-20 | — | — | US | disclosed |