Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL2 | P10415 | 1/20 | 0.39 |
| ▸ | IMPDH2 | P12268 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.38 |
| ▸ | TUBB | P07437 | 1/20 | 0.38 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.38 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.38 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.38 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.38 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.38 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.38 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.38 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7054725 | 0.80 | IMPDH2 (0.38) | BCL2IMPDH2MAPK1HSD17B10MAPT | |
| SCHEMBL8575892 | 0.74 | ENPP3 (0.34) | MAPK1HSD17B10MAPTSMN1; SMN2NPC1 | |
| SCHEMBL8574024 | 0.69 | CHRNB2 (0.35) | — | |
| SCHEMBL6657790 | 0.68 | CYP1A2 (0.37) | MAPK1HSD17B10MAPTSMN1; SMN2MEN1 | |
| SCHEMBL1202543 | 0.68 | IMPDH2 (0.63) | IMPDH2MAPK1HSD17B10MAPTSMN1; SMN2 | |
| SCHEMBL8432119 | 0.68 | ATM (0.41) | IMPDH2MAPK1HSD17B10MAPTSMN1; SMN2 | |
| SCHEMBL22044988 | 0.67 | ATM (0.61) | IMPDH2MAPK1HSD17B10MAPTSMN1; SMN2 | |
| SCHEMBL29713628 | 0.67 | ATM (0.61) | IMPDH2MAPK1HSD17B10MAPTSMN1; SMN2 | |
| SCHEMBL689942 | 0.65 | DHFR (0.38) | MAPK1HSD17B10MAPTSMN1; SMN2NPC1 | |
| SCHEMBL11571300 | 0.64 | NR3C1 (0.44) | IMPDH2MAPK1HSD17B10MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5942459-A | ALUMOXANE-FREE MIXTURE OF TRANSITION METAL METALLOCENE, ORGANOALUMINUM COMPOUND, BORIC ACID-CONTAINING POWDER | MITSUBISHI CHEMICAL CORPORATION (JP) | 1999-08-24 | — | — | US | disclosed |