Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOS | P01100 | 1/20 | 0.40 |
| ▸ | TTR | P02766 | 1/20 | 0.40 |
| ▸ | JUN | P05412 | 1/20 | 0.40 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.40 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.40 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 3/20 | 0.38 |
| ▸ | LDHA | P00338 | 1/20 | 0.36 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.36 |
| ▸ | MMP1 | P03956 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.33 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | PPARD | Q03181 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13548297 | 0.77 | FOS (0.50) | FOSTTRJUNNR3C1HSD17B1 | |
| SCHEMBL806723 | 0.71 | CA2 (0.63) | FOSTTRJUNNR3C1HSD17B1 | |
| SCHEMBL8595058 | 0.71 | FOS (0.44) | FOSTTRJUNNR3C1HSD17B1 | |
| SCHEMBL11153867 | 0.70 | ALDH1A1 (0.53) | FOSTTRJUNNR3C1HSD17B1 | |
| SCHEMBL18269146 | 0.69 | GABRA1 (0.52) | FOSTTRJUNNR3C1HSD17B1 | |
| SCHEMBL6126233 | 0.69 | FOS (0.51) | FOSTTRJUNNR3C1HSD17B1 | |
| SCHEMBL10339014 | 0.68 | LDHA (0.54) | FOSTTRJUNNR3C1HSD17B1 | |
| SCHEMBL58055 | 0.68 | CALM1 (0.58) | FOSTTRJUNNR3C1HSD17B1 | |
| SCHEMBL8114065 | 0.68 | FOS (0.44) | FOSTTRJUNNR3C1HSD17B1 | |
| SCHEMBL12120763 | 0.67 | ALOX15 (0.50) | FOSTTRJUNNR3C1HSD17B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998057910-A2 | CYCLOOXYGENASE-I SELECTIVE INHIBITORS AND THE USE THEREOF AS ANALGESIC, ANTIINFLAMMATORY AND ANTIARTHRITIC AGENTS | LABORATORIOS MENARINI S.A. (ES) | 1998-12-23 | — | — | WO | disclosed |