Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2B | P29275 | 3/20 | 0.35 |
| ▸ | KMO | O15229 | 2/20 | 0.34 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.32 |
| ▸ | CDY1; CDY1B | Q9Y6F8 | 4/20 | 0.32 |
| ▸ | CDYL2 | Q8N8U2 | 3/20 | 0.32 |
| ▸ | CBX7 | O95931 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | PDE4A | P27815 | 1/20 | 0.31 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.31 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.31 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.31 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.31 |
| ▸ | EGFR | P00533 | 1/20 | 0.31 |
| ▸ | CDYL | Q9Y232 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8917032 | 0.88 | CYP1A2 (0.36) | KMOSIGMAR1SLC6A2HTR2ASLC6A4 | |
| SCHEMBL8627148 | 0.80 | PDE4B (0.36) | ADORA2BKMOCDY1; CDY1BCBX7KDM4E | |
| SCHEMBL8626905 | 0.76 | ALDH1A1 (0.43) | ADORA2BPDE1BSIGMAR1SLC6A2HTR2A | |
| SCHEMBL8918738 | 0.76 | ALDH1A1 (0.50) | SIGMAR1KDM4EALDH1A1 | |
| SCHEMBL8918560 | 0.75 | LMNA (0.38) | PDE1BSIGMAR1SLC6A2HTR2ASLC6A4 | |
| SCHEMBL8918139 | 0.67 | HSD17B10 (0.38) | KMOALDH1A1PDE4APDE4BPDE4C | |
| SCHEMBL8917897 | 0.65 | SIGMAR1 (0.42) | SIGMAR1KDM4EALDH1A1 | |
| SCHEMBL8625701 | 0.64 | ALDH1A1 (0.40) | SIGMAR1KDM4EALDH1A1 | |
| SCHEMBL8625029 | 0.64 | NPC1 (0.48) | KDM4EALDH1A1 | |
| SCHEMBL23339264 | 0.62 | SLC6A2 (0.48) | SIGMAR1SLC6A2HTR2ASLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5767128-A | ANALGESICS | ADIR ET COMPAGNIE (FR) | 1998-06-16 | — | — | US | disclosed |
| US-5618819-A | ANALGESICS | ADIR ET COMPAGNIE (FR) | 1997-04-08 | — | — | US | disclosed |
| EP-0691339-A1 | Amine derivatives of 1,3-dihydro-2H-pyrrolo(2,3-b)pyridin-2-ones and oxazolo(4,5-b)pyridin-2(3H)-ones, their process of preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1996-01-10 | — | — | EP | disclosed |