Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | GSK3B | P49841 | 5/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | SPR | P35270 | 2/20 | 0.31 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | KCNJ1 | P48048 | 2/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8917897 | 0.87 | SIGMAR1 (0.42) | ALDH1A1HPGDKDM4ESIGMAR1L3MBTL1 | |
| SCHEMBL8626905 | 0.82 | ALDH1A1 (0.43) | ALDH1A1HPGDKDM4ESIGMAR1HSD17B10 | |
| SCHEMBL8919469 | 0.82 | MAPK1 (0.36) | ALDH1A1HPGDSIGMAR1HSD17B10 | |
| SCHEMBL8624806 | 0.80 | HSD17B10 (0.35) | ALDH1A1HPGDKDM4EHSD17B10L3MBTL1 | |
| SCHEMBL8629045 | 0.79 | ALDH1A1 (0.41) | ALDH1A1SIGMAR1HSD17B10POLBMEN1 | |
| SCHEMBL8919157 | 0.78 | ALDH1A1 (0.35) | ALDH1A1HPGDKDM4ESIGMAR1MEN1 | |
| SCHEMBL8626022 | 0.78 | ALDH1A1 (0.63) | ALDH1A1HPGDKDM4ESIGMAR1HSD17B10 | |
| SCHEMBL8625029 | 0.76 | NPC1 (0.48) | ALDH1A1HPGDKDM4EHSD17B10L3MBTL1 | |
| SCHEMBL8948117 | 0.74 | ALDH1A1 (0.62) | ALDH1A1HPGDGSK3BKDM4ESIGMAR1 | |
| SCHEMBL7328412 | 0.74 | HSD17B10 (0.53) | ALDH1A1HPGDGSK3BKDM4EHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5767128-A | ANALGESICS | ADIR ET COMPAGNIE (FR) | 1998-06-16 | — | — | US | disclosed |
| US-5618819-A | ANALGESICS | ADIR ET COMPAGNIE (FR) | 1997-04-08 | — | — | US | disclosed |
| EP-0691339-A1 | Amine derivatives of 1,3-dihydro-2H-pyrrolo(2,3-b)pyridin-2-ones and oxazolo(4,5-b)pyridin-2(3H)-ones, their process of preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1996-01-10 | — | — | EP | disclosed |