Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 11/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 9/20 | 0.36 |
| ▸ | CASP1 | P29466 | 8/20 | 0.36 |
| ▸ | CASP7 | P55210 | 8/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.36 |
| ▸ | HPGD | P15428 | 4/20 | 0.36 |
| ▸ | KMO | O15229 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | USP2 | O75604 | 3/20 | 0.34 |
| ▸ | PDE4A | P27815 | 1/20 | 0.34 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.34 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.34 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8624599 | 0.88 | ADORA2B (0.35) | ALDH1A1KMOPDE4APDE4BPDE4C | |
| SCHEMBL8918139 | 0.81 | HSD17B10 (0.38) | CYP1A2ALDH1A1HSD17B10CASP1CASP7 | |
| SCHEMBL8918738 | 0.79 | ALDH1A1 (0.50) | ALDH1A1HPGDMAPK1MAPTMEN1 | |
| SCHEMBL8918560 | 0.78 | LMNA (0.38) | ALDH1A1MAPK1MEN1KMT2ASIGMAR1 | |
| SCHEMBL8626905 | 0.77 | ALDH1A1 (0.43) | ALDH1A1HSD17B10HPGDMAPTSIGMAR1 | |
| SCHEMBL8918012 | 0.76 | MIF (0.47) | ALDH1A1HSD17B10HPGDMAPTTP53 | |
| SCHEMBL8627148 | 0.67 | PDE4B (0.36) | ALDH1A1HSD17B10HPGDKMOMAPK1 | |
| SCHEMBL8917897 | 0.66 | SIGMAR1 (0.42) | ALDH1A1HPGDMAPK1SIGMAR1GAA | |
| SCHEMBL8625701 | 0.65 | ALDH1A1 (0.40) | ALDH1A1HSD17B10HPGDMEN1KMT2A | |
| SCHEMBL8919469 | 0.63 | MAPK1 (0.36) | ALDH1A1HSD17B10HPGDMAPK1SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5618819-A | ANALGESICS | ADIR ET COMPAGNIE (FR) | 1997-04-08 | — | — | US | disclosed |
| EP-0691339-A1 | Amine derivatives of 1,3-dihydro-2H-pyrrolo(2,3-b)pyridin-2-ones and oxazolo(4,5-b)pyridin-2(3H)-ones, their process of preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1996-01-10 | — | — | EP | disclosed |