Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 5/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | APP | P05067 | 1/20 | 0.40 |
| ▸ | PDE5A | O76074 | 3/20 | 0.39 |
| ▸ | PDE6C | P51160 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8919157 | 0.87 | ALDH1A1 (0.35) | ALDH1A1MAPTMEN1KMT2AHTT | |
| SCHEMBL8919693 | 0.85 | POLB (0.46) | ALDH1A1MAPTMEN1KMT2AAPP | |
| SCHEMBL8918109 | 0.83 | ALDH1A1 (0.50) | ALDH1A1MAPTMAPK1HTT | |
| SCHEMBL8919271 | 0.83 | ALDH1A1 (0.53) | ALDH1A1MAPTMAPK1KMT2AAPP | |
| SCHEMBL8920278 | 0.80 | MEN1 (0.51) | ALDH1A1MAPK1HRH3MEN1KMT2A | |
| SCHEMBL8917897 | 0.80 | SIGMAR1 (0.42) | ALDH1A1MAPK1SIGMAR1 | |
| SCHEMBL8625701 | 0.79 | ALDH1A1 (0.40) | ALDH1A1MEN1KMT2AHSD17B10POLB | |
| SCHEMBL8917938 | 0.78 | PDE1B (0.43) | ALDH1A1HRH3MEN1KMT2AHTT | |
| SCHEMBL8918611 | 0.77 | SIGMAR1 (0.41) | ALDH1A1SIGMAR1 | |
| SCHEMBL8919198 | 0.77 | POLB (0.47) | ALDH1A1MAPTHSD17B10POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5767128-A | ANALGESICS | ADIR ET COMPAGNIE (FR) | 1998-06-16 | — | — | US | disclosed |
| US-5618819-A | ANALGESICS | ADIR ET COMPAGNIE (FR) | 1997-04-08 | — | — | US | disclosed |
| EP-0691339-A1 | Amine derivatives of 1,3-dihydro-2H-pyrrolo(2,3-b)pyridin-2-ones and oxazolo(4,5-b)pyridin-2(3H)-ones, their process of preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1996-01-10 | — | — | EP | disclosed |