Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 4/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.59 |
| ▸ | MEN1 | O00255 | 3/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.58 |
| ▸ | MAPT | P10636 | 3/20 | 0.58 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.55 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.52 |
| ▸ | THRB | P10828 | 1/20 | 0.52 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.52 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8712014 | 0.95 | ALDH1A1 (0.56) | POLBKMT2AMEN1ALDH1A1MAPT | |
| SCHEMBL2836012 | 0.83 | POLB (0.63) | POLBKMT2AMEN1ALDH1A1MAPT | |
| SCHEMBL7778609 | 0.80 | ALDH1A1 (0.66) | POLBKMT2AMEN1ALDH1A1MAPT | |
| SCHEMBL8631484 | 0.78 | RAB9A (0.57) | POLBKMT2AMEN1ALDH1A1MAPT | |
| SCHEMBL8629515 | 0.78 | ATF4 (0.56) | KMT2AMEN1ALDH1A1 | |
| SCHEMBL8628965 | 0.78 | LMNA (0.56) | KMT2AMEN1ALDH1A1MAPTTHRB | |
| SCHEMBL14846355 | 0.78 | ALDH1A1 (0.68) | POLBKMT2AMEN1ALDH1A1MAPT | |
| SCHEMBL432126 | 0.78 | CYP19A1 (0.67) | POLBKMT2AMEN1ALDH1A1MAPT | |
| SCHEMBL3999404 | 0.78 | ALDH1A1 (0.76) | POLBKMT2AMEN1ALDH1A1MAPT | |
| SCHEMBL11431170 | 0.77 | PLA2G4B (0.68) | POLBKMT2AMEN1ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5840917-A | ADMINISTERING TO MAMMAL TO ERADICATE HELICOBACTER PYLORI | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1998-11-24 | — | — | US | disclosed |
| WO-1998042347-A1 | PHARMACEUTICAL COMPOSITION CONTAINING A PHOSPHORYLAMIDE AND AN AYNTIBIOTIC | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1998-10-01 | — | — | WO | disclosed |
| EP-0852498-A1 | PHOSPHORYLAMIDES, THEIR PREPARATION AND USE | Takeda Chemical Industries, Ltd. (JP) | 1998-07-15 | — | — | EP | disclosed |
| WO-1997011705-A1 | PHOSPHORYLAMIDES, THEIR PREPARATION AND USE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1997-04-03 | — | — | WO | disclosed |